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928062

Sigma-Aldrich

Gold nanoparticles

5 nm diameter, alkyne functionalized, 1 ML, OD 50, in water

Synonym(s):

AuNP, GdNP, Gold NP

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About This Item

UNSPSC Code:
12141717
NACRES:
NA.22

Quality Level

100

description

Alkyne surface density: 1/nm2

concentration

in water

OD

50

core diam.

5 nm , coefficient of variance <12%

diameter

5 nm

λmax

515-520 nm

PDI

<0.200

functional group

alkyne

storage temp.

2-8°C

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Alkyne functionalized gold nanoparticles are suitable for covalent conjugation of any azide-tagged molecule through Cu(I)-catalyzed click chemistry. These gold nanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays.
Alkyne functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).

Application

Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).

Storage and Stability

When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gold Nanoparticles: Synthesis and Applications in Drug Delivery.
Khan A K, et al.
Tropical Journal of Pharmaceutical Research, 7, 1169-1177 (2014)
Wilson Luo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(5), 1052-1059 (2016-10-12)
In this study, we report the design, synthesis, and characterization of small 3 nm water soluble gold nanoparticles (AuNPs) that feature cyclopropenone-masked strained alkyne moieties capable of undergoing interfacial strain-promoted cycloaddition (i-SPAAC) with azides after exposure to UV-A light. A strained
Mingmin Li et al.
Nanotheranostics, 3(1), 113-119 (2019-03-23)
Surface-enhanced Raman spectroscopy (SERS) has proven a powerful tool for multiplex detection and imaging due to its narrow peak width and high sensitivity. However, conventional SERS reporters are limited to thiolated compounds, which have limitations such as chemical stability and

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