A16602
DL-N-Acetylhomocysteine thiolactone
98%
Synonym(s):
2-Acetamido-4-mercaptobutyric acid γ-thiolactone
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C6H9NO2S
CAS Number:
Molecular Weight:
159.21
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
powder
mp
109-111 °C (lit.)
SMILES string
CC(=O)NC1CCSC1=O
InChI
1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8)
InChI key
NRFJZTXWLKPZAV-UHFFFAOYSA-N
Application
<ul>
<li><strong>Ultrasonic synthesis of stable oil filled microcapsules:</strong> This study explores the ultrasonic synthesis of oil-filled microcapsules using thiolated chitosan, potentially involving derivatives like N-Acetylhomocysteine thiolactone for improved stability and functional properties. The research provides insights into advanced microencapsulation techniques relevant in pharmaceutical and industrial applications (
<li><strong>Ultrasonic synthesis of stable oil filled microcapsules:</strong> This study explores the ultrasonic synthesis of oil-filled microcapsules using thiolated chitosan, potentially involving derivatives like N-Acetylhomocysteine thiolactone for improved stability and functional properties. The research provides insights into advanced microencapsulation techniques relevant in pharmaceutical and industrial applications (
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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S M Naqvi et al.
Neuroreport, 2(1), 61-63 (1991-01-01)
The present study was undertaken to evaluate the neurotoxic effects of the organophosphate, phosphamidon, on glutathione-S-transferase (GST) activity and concentration of sulphhydryl groups, and to study the possible protection against these effects by the simultaneous administration of the antioxidant, acetylhomocysteine
G Papaccio et al.
Journal of cellular biochemistry, 71(4), 479-490 (1998-11-25)
This study showed that citiolone (CIT), a free radical scavenger, significantly increased superoxide dismutase (P < 0.001 vs. untreated NOD, NMMA-treated, and silica-treated animals), catalase (P < 0.01 vs. untreated NOD), and glutathione peroxidase (P < 0.001 vs. untreated NOD
N Emonet et al.
Journal of photochemistry and photobiology. B, Biology, 40(1), 84-90 (1997-08-01)
The sensitivity of human dermal fibroblasts to UVA radiation has been linked to a decrease in intracellular glutathione (GSH) levels. GSH (gamma-glutamyl-cysteinyl-glycine) is a radical scavenger and a cofactor for protective enzymes such as selenium-dependent GSH peroxidases. In this study
Comparison of monothiols and vitamin therapy administered alone or in combinations during methylmercury poisoning.
C Bapu et al.
Bulletin of environmental contamination and toxicology, 52(2), 182-189 (1994-02-01)
C Bapu et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 17(1), 75-80 (1998-03-07)
The aim of our investigation was to examine the efficacy of monothiols and vitamins in the restoration of ion-dependent ATPases in mice intoxicated with methylmercury chloride (MMC). A daily dose of glutathione (GSH), N-acetyl-DL-homocysteine thiolactone (NAHT), vitamin B complex, or
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