W313718

2,6-Dimethoxyphenol

≥98%, FG

• Synonym(s): Pyrogallol 1,3-dimethyl ether
• Linear Formula: (CH₃O)₂C₆H₃OH
• CAS Number: 91-10-1
• Molecular Weight: 154.16
• FEMA Number: 3137
• Beilstein: 1526871
• EC Number: 202-041-1
• Council of Europe no.: 2233
• MDL number: MFCD00064434
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901483
• Flavis number: 4.036
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Fragrance grade; Halal; Kosher
• Agency: follows IFRA guidelines; meets purity specifications of JECFA
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002
• Assay: ≥98%
• bp: 261 °C (lit.)
• mp: 50-57 °C (lit.)
• application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: no known allergens
• Organoleptic: bacon; meaty; smoky; woody; balsamic; phenolic
• SMILES string: COc1cccc(OC)c1O
• InChI: 1S/C8H10O3/c1-10-6-4-3-5-7(11-2)8(6)9/h3-5,9H,1-2H3
• InChI key: KLIDCXVFHGNTTM-UHFFFAOYSA-N

Description

General description

2,6-Dimethoxyphenol has been identified as one of the volatile flavor constituents in shoyu (soy sauce), wine and wood smoke.

Application

• 3,3′,5,5′-Tetramethoxybiphenyl-4,4′diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-κB pathway in the NCI-H460 lung cancer cell line.: Investigates a derivative of 2,6-Dimethoxyphenol for its anti-cancer properties, offering a new avenue for therapeutic research against lung cancer (Concato-Lopes et al., 2024).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 284.0 °F - closed cup
• Flash Point(C): 140 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves