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850702P

Avanti

12:0 PE

1,2-dilauroyl-sn-glycero-3-phosphoethanolamine, powder

Synonym(s):

1,2-didodecanoyl-sn-glycero-3-phosphoethanolamine; DLPE; PE(12:0/12:0)

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About This Item

Empirical Formula (Hill Notation):
C29H58NO8P
CAS Number:
59752-57-7
Molecular Weight:
579.75
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850702P-1g)
pkg of 1 × 200 mg (850702P-200mg)
pkg of 1 × 25 mg (850702P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850702P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O

InChI

1S/C29H58NO8P/c1-3-5-7-9-11-13-15-17-19-21-28(31)35-25-27(26-37-39(33,34)36-24-23-30)38-29(32)22-20-18-16-14-12-10-8-6-4-2/h27H,3-26,30H2,1-2H3,(H,33,34)

InChI key

ZLGYVWRJIZPQMM-UHFFFAOYSA-N

General description

Phosphatidylethanolamine (PE) is one of the widely distributed glycerophospholipid in eukaryotic cells. 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine (12:0 PE/DLPE) possess an ammonium head group (RNH3+) and has alkyl chains made of 11 carbon atoms.

Application

1,2-dilauroyl-sn-glycero-3-phosphoethanolamine (12:0 PE):
  • has been used as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions
  • may be used as a phospholipid (PL) standard to quantify phosphatidylethanolamine (PE) from plant lipids
  • may be used to prepare anionic liposomes
  • may be used to prepare binary giant unilamellar vesicles (GUVs)

Biochem/physiol Actions

Phosphatidylethanolamine (PE) plays a vital role in the structure and function of eukaryotic membranes.

Packaging

20 mL Clear Glass Screw Cap Vial (850702P-1g)
5 mL Amber Glass Screw Cap Vial (850702P-200mg)
5 mL Amber Glass Screw Cap Vial (850702P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Oligonucleotide delivery with serum into HeLa cells using polycation liposomes
Mady MM
Journal of Biomedical Materials Research. Part B, Applied Biomaterials, 7(1), 69-69 (2007)
The influence of DOPC on the permeability of lipid membrane: Detergent solubilization and NMR study
Mady MM
Romanian Journal of Biophysics, 17, 259-267 (2007)
Takehiro Jimbo et al.
Biophysical journal, 110(7), 1551-1562 (2016-04-14)
We investigate a temperature-driven recursive division of binary giant unilamellar vesicles (GUVs). During the heating step of the heating-cooling cycle, the spherical mother vesicle deforms to a budded limiting shape using up the excess area produced by the chain melting
Phosphatidylethanolamine metabolism in health and disease
International Review of Cell and Molecular Biology, 321, 29-88 (2016)
K V Damodaran et al.
Biophysical journal, 66(4), 1076-1087 (1994-04-01)
A 250 ps molecular dynamics simulation of the dimyristoylphosphatidylcholine (DMPC)-based lipid bilayer, including explicit water molecules, is reported. The solvent environment of the head groups and other structural properties of the bilayer have been analyzed and compared with experimental results
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