H-049

Hydromorphone-D₆ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₇H₁₃NO₃D₆
• CAS Number: 1024922-02-8
• Molecular Weight: 291.37
• EC Number: 200-659-6
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: 2-8°C
• SMILES string: [2H]C1N([C@@H]2Cc3ccc(O)c4O[C@H]5C(=O)CC[C@@H]2[C@]5(c34)C1([2H])[2H])C([2H])([2H])[2H]
• InChI: 1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,16,19H,3,5-8H2,1H3/t10-,11+,16-,17-/m0/s1/i1D3,6D2,7D/t7?,10-,11+,16-,17-
• InChI key: WVLOADHCBXTIJK-LJWMZWAHSA-N

Description

General description

Hydromorphone, marketed under brand names including Palladone and Dilaudid^®, is a very potent opiate used as an analgesic for treating pain or as a cough suppressant for painful coughing resulting from continued bronchial irritation. This Certified Spiking Solution^® is suitable for isotope dilution methods or quantitation of hydromorphone levels by GC/MS or LC/MS for clinical toxicology, pain prescription monitoring, urine drug testing, or pharmaceutical research applications.

Application

• Hydromorphone-D6 as an internal standard in opioid research: Hydromorphone-D6 solution is utilized as a stable isotope-labeled internal standard for the quantification of hydromorphone in human plasma via liquid chromatography-tandem mass spectrometry. This application supports the precise measurement of opioid concentrations in pharmacokinetic studies and aids in the development of bioanalytical methods for drug monitoring and research (Valtier et al., 2013).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Dilaudid is a registered trademark of Purdue Pharma L.P.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup