N-115

Naloxone-D₅ solution

1.0 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₉H₁₆NO₄D₅
• CAS Number: 1261079-38-2
• Molecular Weight: 332.41
• MDL number: MFCD08063611
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: [2H]\C([2H])=C(/[2H])C([2H])([2H])N1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35
• InChI: 1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1/i1D2,2D,8D2
• InChI key: UZHSEJADLWPNLE-HEEDNVRVSA-N

Description

General description

A stable-labeled internal standard suitable for numerous quantitative LC/MS and GC/MS applications in forensic analysis, clinical toxicology testing, pharmaceutical analysis and isotope dilution methods. Naloxone is an opiate drug used to counter the effects of opioid overdose.

Application

• Naloxone-D₅ analytical standard: Naloxone-D₅ is a stable isotopic label extensively utilized as an analytical standard in mass spectrometry to study the pharmacokinetics of naloxone. This application is critical for understanding naloxone′s metabolism and clearance rates in opioid overdose scenarios, thereby enhancing therapeutic strategies and drug safety (Xu et al., 2018).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup