1.00552

ortho-Phosphoric acid

85%, Suprapur^®

• Synonym(s): Phosphoric acid, o-Phosphoric acid, Orthophosphoric acid, Orthophosphoric acid
• Linear Formula: H₃PO₄
• CAS Number: 7664-38-2
• Molecular Weight: 98.00
• Beilstein: 1921286
• MDL number: MFCD00011340
• UNSPSC Code: 12352301
• NACRES: NB.21

Properties

• product name: ortho-Phosphoric acid 85%, Suprapur^®
• grade: for inorganic trace analysis
• Quality Level: 100
• vapor density: 3.4 (vs air)
• vapor pressure: 2.2 mmHg ( 20 °C); 5 mmHg ( 25 °C)
• Assay: 85%
• form: liquid
• pH: <0.5 (20 °C, 100 g/L in H₂O)
• kinematic viscosity: 30.5 cSt(20 °C)
• bp: 158 °C (lit.)
• mp: ~40 °C (lit.)
• density: 1.685 g/mL at 25 °C (lit.)
• storage temp.: no temp limit
• SMILES string: OP(O)(O)=O
• InChI: 1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
• InChI key: NBIIXXVUZAFLBC-UHFFFAOYSA-N

Description

Application

• Development of green micellar HPLC-DAD method for simultaneous determination of some sulbactam combinations used in COVID-19 regimen: This study presents a green analytical methodology utilizing micellar high-performance liquid chromatography with diode-array detection (HPLC-DAD). It is specifically employed for the simultaneous determination of sulbactam and other compounds in COVID-19 treatment regimens, showcasing an application of ortho-Phosphoric acid in adjusting the pH of the mobile phase to enhance analytical performance and separation efficiency (Ragab GH, Saleh HM, Abdulla NM, Bahgat EA, 2023).

Other Notes

Concentrated phosphoric acid is approx. 85% H₃PO₄ (aqueous).

Linkage

Replaces: 552; 552-2; 552-3

Analysis Note

Assay (acidimetric): ≥ 85.0 %
Chloride (Cl): ≤ 500 ppb
Fluoride (F): ≤ 500 ppb
Nitrate (NO₃): ≤ 500 ppb
Sulphate (SO₄): ≤ 10 ppm
Ag (Silver): ≤ 20 ppb
Al (Aluminium): ≤ 20 ppb
As (Arsenic): ≤ 25 ppb
Au (Gold): ≤ 20 ppb
Ba (Barium): ≤ 20 ppb
Be (Beryllium): ≤ 50 ppb
Bi (Bismuth): ≤ 50 ppb
Ca (Calcium): ≤ 50 ppb
Cd (Cadmium): ≤ 20 ppb
Co (Cobalt): ≤ 20 ppb
Cr (Chromium): ≤ 50 ppb
Cu (Copper): ≤ 25 ppb
Fe (Iron): ≤ 200 ppb
Hg (Mercury): ≤ 2 ppb
K (Potassium): ≤ 50 ppb
Li (Lithium): ≤ 20 ppb
Mg (Magnesium): ≤ 20 ppb
Mn (Manganese): ≤ 20 ppb
Mo (Molybdenum): ≤ 20 ppb
Na (Sodium): ≤ 100 ppb
Ni (Nickel): ≤ 25 ppb
Pb (Lead): ≤ 20 ppb
Pt (Platinum): ≤ 100 ppb
Sb (Antimony): ≤ 800 ppb
Sn (Tin): ≤ 50 ppb
Sr (Strontium): ≤ 20 ppb
Tl (Thallium): ≤ 20 ppb
V (Vanadium): ≤ 20 ppb
Zn (Zinc): ≤ 25 ppb
Zr (Zirconium): ≤ 50 ppb
The actual values are subject to unavoidable systematic
variations in this concentration range.

Legal Information

SUPRAPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H290 - H302 - H314
• Precautionary Statements: P234 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Storage Class Code: 8B - Non-combustible, corrosive hazardous materials
• WGK: WGK 1