1.07478

1,2-Propanediol

EMPROVE^® EXPERT, Ph. Eur., BP, USP

• Synonym(s): 1,2-Propanediol, 1,2-Propylene glycol
• Linear Formula: CH₃CH(OH)CH₂OH
• CAS Number: 57-55-6
• Molecular Weight: 76.09
• MDL number: MFCD00064272
• UNSPSC Code: 12352104
• EC Index Number: 200-338-0

Properties

• Agency: BP; Ph. Eur.; USP
• Quality Level: 500
• vapor pressure: 0.11 hPa ( 20 °C)
• product line: EMPROVE^® EXPERT
• Assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 371 °C
• expl. lim.: 2.4-17.4 % (v/v)
• refractive index: n20/D 1.43
• pH: 6-8 (20 °C, 100 g/L in H₂O)
• bp: 188 °C/1013 hPa
• mp: -59 °C
• transition temp: flash point 99 °C
• density: 1.04 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; parenterals; parenterals; pharmaceutical; semi-solid formulation
• storage temp.: 2-30°C
• InChI: 1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
• InChI key: DNIAPMSPPWPWGF-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propylene glycol is used as solvent in a variety of liquid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 219.2 °F - closed cup
• Flash Point(C): 104 °C - closed cup