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420318

Sigma-Aldrich

Kainic Acid

≥98% (HPLC), solid, amino acid receptor agonist, Calbiochem®

Synonym(s):

Kainic Acid, 2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid

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About This Item

Empirical Formula (Hill Notation):
C10H15NO4
CAS Number:
487-79-6
Molecular Weight:
213.23
UNSPSC Code:
12352106
NACRES:
NA.77

product name

Kainic Acid, An excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for ³H-kainate binding in rat striatum).

Quality Level

200

Assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

off-white

solubility

dilute base: 10 mg/mL
water: 10 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1

InChI key

VLSMHEGGTFMBBZ-OOZYFLPDSA-N

General description

An excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for 3H-kainate binding in rat striatum). Also activates AMPA receptors.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Kainate receptor subtype
Product does not compete with ATP.
Reversible: no
Target Ki: 21 nM for 3H-kainate binding in rat striatum

Warning

Toxicity: Harmful (C)

Other Notes

Niu, L., et al. 1996. Biochemistry35, 2030.
Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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