539215

Protein C, Human Plasma

• UNSPSC Code: 12352202
• NACRES: NA.25

Properties

• Assay: ≥95% (SDS-PAGE)
• Quality Level: 100
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Native protein C from human plasma. Sold as a zymogen. Markedly prolongs kaolin-cephalin clotting time of normal plasma. Activated by α-thrombin to serine protease-activated protein C. In its active form, it is a potent anticoagulant that acts through selective inactivation of Factors Va and VIIIa.

Warning

Toxicity: Standard Handling (A)

Physical form

In 100 mM NaCl, 20 mM Tris-HCl, 1 mM benzamidine, pH 7.4.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Esmon, N.L., et al. 1999. Haematologica 84, 363.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable