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Key Documents

AB5566

Sigma-Aldrich

Anti-Capsaicin Receptor Antibody, CT

serum, Chemicon®

Synonym(s):

Vanilloid Receptor 1, VR1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

guinea pig

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TRPV1(7442)

Specificity

Recognizes Capsaicin Receptor (Vanilloid Receptor 1, VR1).

Immunogen

A 22 amino acid peptide corresponding to the C-terminus of the rat Capsaicin Receptor protein (Catalog number AG298).

Application

Anti-Capsaicin Receptor Antibody, C-terminus detects level of Capsaicin Receptor & has been published & validated for use in IH.
Immunohistochemistry: 1:1,000. The antibody reacts well with tissue from the rat dorsal root ganglia.

Optimal working dilutions must be determined by end user.

Physical form

Serum. Liquid. Contains less than 0.02% sodium azide.

Analysis Note

Control
Immunogen peptide (catalog number AG298) is available for preadsorbtion control studies.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sam M Hermes et al.
Journal of chemical neuroanatomy, 72, 1-7 (2015-12-27)
The vagus nerve is dominated by afferent fibers that convey sensory information from the viscera to the brain. Most vagal afferents are unmyelinated, slow-conducting C-fibers, while a smaller portion are myelinated, fast-conducting A-fibers. Vagal afferents terminate in the nucleus tractus
Yumi Matsushita et al.
The Journal of veterinary medical science, 83(10), 1570-1581 (2021-09-03)
The activation of α2 adrenergic receptors contributes to analgesia not only in the central nervous system but also in the peripheral nervous system. We reported that noradrenaline inhibits the activity of transient receptor potential vanilloid 1 (TRPV1) evoked by capsaicin
S-Q He et al.
Neuroscience, 261, 43-51 (2014-01-01)
Mas-related G-protein-coupled receptor subtype C (MrgC) may play an important role in pain sensation. However, the distribution of MrgC receptors in different subpopulations of rodent dorsal root ganglion (DRG) neurons has not been clearly demonstrated owing to a lack of
Gyu-Sang Hong et al.
Neuron, 91(1), 107-118 (2016-06-21)
Touch sensation or proprioception requires the transduction of mechanical stimuli into electrical signals by mechanoreceptors in the periphery. These mechanoreceptors are equipped with various transducer channels. Although Piezo1 and 2 are mechanically activated (MA) channels with rapid inactivation, MA molecules
Na-Xi Tian et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(7), 1756-1773 (2018-01-18)
Potassium voltage-gated channel interacting protein 3 (KChIP3), also termed downstream regulatory element antagonist modulator (DREAM) and calsenilin, is a multifunctional protein belonging to the neuronal calcium sensor (NCS) family. Recent studies revealed the expression of KChIP3 in dorsal root ganglion

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