HNDG1MAG-36K

MILLIPLEX^® Human Neurodegenerative Disease Magnetic Bead Panel 1 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: α2-Macroglobulin, Apo Al, Apo CIII, Apo E, Complement C3 and Complement Factor H.

• UNSPSC Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

Properties

• Quality Level: 200
• species reactivity: human
• manufacturer/tradename: Milliplex^®
• assay range: accuracy: 105%; (Complement Factor H); accuracy: 110%; (Apo E); accuracy: 75%; (Complement C3); intra-assay cv: <10; standard curve range: 0.01-40 ng/mL; (Apo CIII); standard curve range: 0.05-200 ng/mL; (Apo E, Complement C3); standard curve range: 0.3-1,000 ng/mL; (Complement Factor H); standard curve range: 0.5-2,000 ng/mL; (α-2-Macroglobulin); standard curve range: 0.7-3,000 ng/mL; (Apo A1)
• technique(s): multiplexing: suitable
• detection method: fluorometric (Luminex xMAP)
• shipped in: wet ice

Description

General description

Neurodegenerative disease is a condition characterized by the deterioration of neurons or their myelin sheath over time in the brain and/or spinal cord. These neurons are responsible for such everyday activities as processing sensory information, making decisions, and controlling movement. Because these cells are not easily regenerated, excessive cumulative damage can lead to age-related diseases such as Alzheimer′s and Parkinson′s disease, as well as other conditions such as amyotrophic lateral sclerosis (ALS) and epilepsy. These disorders are devastating and expensive, both on a personal and global level, and as population demographics continue to change, a therapeutic solution is critical. Consequently, research is underway to identify biomarkers that will help scientists not only understand the pathogenesis of neurodegenerative disease, but also identify people with these disorders before the onset of symptoms and potentially provide new therapeutic tools.
The “MILLIPLEX” Human Neurodegenerative Bead Panel 1 (HNDG1MAG-36K) is to be used for the simultaneous quantification of the following 7 analytes in any combination: α-2-Macroglobulin, Apo A1, Apo CIII, Apo E, Complement C3 and Complement Factor H. This kit may be used for the analysis of all above analytes in human serum, plasma, and cerebrospinal fluid samples.

Panel Type: Neuroscience

Specificity

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Application

• Analytes: : α2-Macroglobulin, Apo Al, Apo CIII, Apo E, Complement C3, Complement Factor H
• Recommended Sample type: serum, plasma and CSF
• Recommended Sample dilution: 1:40,000 diluted serum/plasma or 1:400 diluted CSF per well
• Assay Run Time: One day
• Research Category: Neuroscience

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Packaging

Everything you need in a single kit.

Storage and Stability

Recommended storage for kit components is 2 - 8°C.

Other Notes

Sensitivity: See protocol for sensitivities of individual analytes

Legal Information

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Pictograms: GHS08,GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302 + H312 + H332,H317,H318,H373,H411
• Precautionary Statements: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Target Organs: Respiratory Tract
• Storage Class Code: 10 - Combustible liquids