MABMAG-83K
MILLIPLEX® Mouse Amyloid Beta Magnetic Bead Panel - Multiplex Assay
for quantification of Aβ40 and Aβ42 in mouse serum, plasma, CSF and tissue culture samples
Sign Into View Organizational & Contract Pricing
All Photos(3)
About This Item
UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.47
Recommended Products
Quality Level
species reactivity
mouse
manufacturer/tradename
Milliplex®
assay range
accuracy: 80%
(Spike recovery for Aβ1-40)
sensitivity: 3.6 pg/mL
(A?1-40; MinDC+2SD)
sensitivity: 4.8 pg/mL
(A?1-42; MinDC+2SD)
standard curve range: 3-2500 pg/mL
(Aβ1-40)
standard curve range: 7-5000 pg/mL
(Aβ1-42)
inter-assay cv: <10%
intra-assay cv: <5%
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex xMAP)
shipped in
ambient
General description
The MILLIPLEX® Mouse Amyloid Beta Bead Panel enables you to evaluate and quantitate Aβ40 and Aβ42 in your mouse research models. Coupled with the Luminex® xMAP® platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, which can dramatically improve productivity.
The MILLIPLEX® Mouse Amyloid Beta Bead Panel is to be used for the simultaneous quantification of Aβ40 and Aβ42. This kit may be used only for the analysis mouse serum, plasma, cerebrospinal fluid (CSF) and tissue culture samples. This is a configurable assay, and one or both analytes can be selected: amyloid β40, amyloid β42. The MILLIPLEX® portfolio offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the validation process include: cross-reactivity, dilution linearity, kit stability and sample behavior (e.g. detectability and stability). Each panel and kit meets stringent manufacturing criteria to ensure batch-to-batch reproducibility.
Each MILLIPLEX® panel and kit includes:
Panel Type: Neuroscience
The MILLIPLEX® Mouse Amyloid Beta Bead Panel is to be used for the simultaneous quantification of Aβ40 and Aβ42. This kit may be used only for the analysis mouse serum, plasma, cerebrospinal fluid (CSF) and tissue culture samples. This is a configurable assay, and one or both analytes can be selected: amyloid β40, amyloid β42. The MILLIPLEX® portfolio offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the validation process include: cross-reactivity, dilution linearity, kit stability and sample behavior (e.g. detectability and stability). Each panel and kit meets stringent manufacturing criteria to ensure batch-to-batch reproducibility.
Each MILLIPLEX® panel and kit includes:
- Quality controls (QCs) provided to qualify assay performance
- Comparison of standard (calibrator) and QC lots to a reference lot to ensure lot-to-lot consistency
- Optimized serum matrix to mimic native analyte environment
- Detection antibody cocktails designed to yield consistent analyte profiles within panel MILLIPLEX® Mouse Amyloid Beta Bead Panel is part of the most versatile system available for your research. From our single to multiplex biomarker solutions, we partner with you to design, develop, analytically validate, and build the most comprehensive library available for protein detection and quantitation.
Panel Type: Neuroscience
Specificity
Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
Application
- Analytes: Amyloid β40, Amyloid β42
- Recommended Sample type: serum, plasma, cerebrospinal fluid (CSF), and tissue culture
- Recommended Sample dilution: 1:2 dilution of serum or plasma, 1:10 dilution of cerebrospinal fluid (CSF), or neat/appropriately diluted tissue culture supernatant
- Assay Run Time:
- Research Category: Neuroscience Metabolism
- Research Subcategory: Category Metabolic Disorders Obesity Inflammation & Autoimmune Mechanisms
Features and Benefits
Design your multiplex kit by choosing available analytes within this panel.
Packaging
96-well plate
Everything you need in a single kit.
Components
Mouse ABeta Standard, 1 vial, lyophilized
Mouse ABeta Quality Control 1, 1 vial, lyophilized
Mouse ABeta Quality Control 2, 1 vial, lyophilized
Serum Matrix (0.08% Sodium Azide) 1 vial, lyophilized
Set of one 96-Well Plate with 2 sealers
Assay Buffer, 1 bottle, 30 mL
Wash Buffer, 10X (0.05% Proclin), 1 bottle, 60 mL
Mouse ABeta Detection Antibody, 1 bottle, 3.2 mL
Streptavidin-Phycoerythrin, 1 bottle, 3.2 mL
Mixing Bottle, 1 bottle
Mouse ABeta Quality Control 1, 1 vial, lyophilized
Mouse ABeta Quality Control 2, 1 vial, lyophilized
Serum Matrix (0.08% Sodium Azide) 1 vial, lyophilized
Set of one 96-Well Plate with 2 sealers
Assay Buffer, 1 bottle, 30 mL
Wash Buffer, 10X (0.05% Proclin), 1 bottle, 60 mL
Mouse ABeta Detection Antibody, 1 bottle, 3.2 mL
Streptavidin-Phycoerythrin, 1 bottle, 3.2 mL
Mixing Bottle, 1 bottle
Storage and Stability
Recommended storage for kit components is 2 - 8°C.
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
Target Organs
Respiratory Tract
Storage Class Code
10 - Combustible liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Gayane Hrachia Buniatian et al.
Cells, 9(2) (2020-02-25)
The function and regulation of amyloid-beta (Aβ) in healthy and diseased liver remains unexplored. Because Aβ reduces the integrity of the blood-brain barrier we have examined its potential role in regulating the sinusoidal permeability of normal and cirrhotic liver. Aβ
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service