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Key Documents

SCT034

Sigma-Aldrich

BioTracker 574 Red HOCL Dye

Live cell imaging dye for hypochlorous acid (HOCl) used to detect phagocytosis, inflammation and cellular apoptosis.

Synonym(s):

Live cell imaging probe

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About This Item

UNSPSC Code:
12352207
eCl@ss:
32161000
NACRES:
NA.47

technique(s)

cell based assay: suitable

detection method

fluorometric

shipped in

ambient

General description

The production of hypochlorous acid (HOCl) by the myeloperoxidase-H2O2-Cl- system of phagocytes plays a vital role in the ability of immune cells to kill a wide range of pathogens including bacteria and viruses. Hypochlorous acid is one of the various reactive oxygen species (ROS) including hydroxyradical (・OH), superoxide (O2-・), hydrogen peroxide (H2O2), singlet oxygen (1O2), nitric oxide (・NO), and peroxynitrite (ONOO-).

The BioTracker 574 Red HOCL Dye is a fluorescent probe that shows excellent selectivity against hypochlorous acid (HOCl) in living cells. The dye contains fast reactivity, slow photobleaching and is suitable for time-lapse live cell imaging.

Spectral Properties
Absorbance: 553nm
Emission: 574nm

Application

Live cell fluorescent imaging
Research Category
Cell Imaging
Research Sub Category
Live Cell Dye

Physical form

Lyophilized

Storage and Stability

Store BioTracker 574 Red HOCL Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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