31730

Diethylamine

puriss. p.a., ≥99.5% (GC)

• Synonym(s): N,N-Diethylamine, N-ethyl-ethanamine, DEA, Diethamine, Diethyl amine
• Linear Formula: (C₂H₅)₂NH
• CAS Number: 109-89-7
• Molecular Weight: 73.14
• Beilstein: 605268
• EC Number: 203-716-3
• MDL number: MFCD00009032
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648605
• NACRES: NA.21

Properties

• vapor density: 2.5 (vs air)
• Quality Level: 200
• vapor pressure: 14.14 psi ( 55 °C); 180 mmHg ( 20 °C); 3.51 psi ( 20 °C)
• grade: puriss. p.a.
• Assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 594 °F
• expl. lim.: 10.1 %
• impurities: ≤0.1% water
• evapn. residue: ≤0.001%
• refractive index: n20/D 1.385 (lit.); n20/D 1.386
• bp: 55 °C (lit.)
• mp: −50 °C (lit.)
• density: 0.707 g/mL at 25 °C (lit.)
• cation traces: Al: ≤0.5 mg/kg; Ba: ≤0.1 mg/kg; Bi: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.02 mg/kg; Cr: ≤0.02 mg/kg; Cu: ≤0.02 mg/kg; Fe: ≤0.1 mg/kg; K: ≤0.5 mg/kg; Li: ≤0.1 mg/kg; Mg: ≤0.1 mg/kg; Mn: ≤0.02 mg/kg; Mo: ≤0.1 mg/kg; Na: ≤0.5 mg/kg; Ni: ≤0.02 mg/kg; Pb: ≤0.1 mg/kg; Sr: ≤0.1 mg/kg; Zn: ≤0.1 mg/kg
• SMILES string: CCNCC
• InChI: 1S/C4H11N/c1-3-5-4-2/h5H,3-4H2,1-2H3
• InChI key: HPNMFZURTQLUMO-UHFFFAOYSA-N

Description

General description

Diethylamine is a secondary amine that is used in the production of pesticides, dyes, rubber, resins, and pharmaceuticals as a solvent, catalyst, and corrosion inhibitor.

Application

Diethylamine can be used as:

• A catalyst in the tandem Knoevenagel-Michael reaction of dimedone with aromatic aldehydes to synthesize bis-dimedone derivatives.
• A solvent to synthesize 4-quinolones via Sonogashira cross-coupling of iodoanilines and alkynes.
• A base in the desymmetrizing cyclization of benzylic diallyl iodide to synthesize methylene indanes via intramolecular Heck reaction.
• A template in the synthesis of silicoaluminophosphate (SAPO) molecular sieves.

Safety Information

• Pictograms: GHS02,GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311,H314,H332,H335
• Precautionary Statements: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): -14.8 °F - closed cup
• Flash Point(C): -26 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves