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Supelco

TEPP

PESTANAL®, analytical standard

Synonym(s):

Tetraethyl pyrophosphate, Tetraethyl diphosphate

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About This Item

Empirical Formula (Hill Notation):
C8H20O7P2
CAS Number:
107-49-3
Molecular Weight:
290.19
Beilstein:
1714017
EC Number:
203-495-3
MDL number:
MFCD00055459
UNSPSC Code:
41116107
PubChem Substance ID:
329754210
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CCOP(=O)(OCC)OP(=O)(OCC)OCC

InChI

1S/C8H20O7P2/c1-5-11-16(9,12-6-2)15-17(10,13-7-3)14-8-4/h5-8H2,1-4H3

InChI key

IDCBOTIENDVCBQ-UHFFFAOYSA-N

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General description

TEPP (Tetraethyl pyrophosphate, Pestanal) is highly toxic in nature both by skin absorption and inhalation. It is an organic phosphate pesticide, acting acts as an inhibitor of cholinesterase. It is soluble in water and is slowly decomposed by water. It may be found as a dry mixture or in the liquid state.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Statements

H300 + H310,H410

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL6667
BCCJ8324
BCBW7851
BCBW3672
BCBT3268

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The role of A-esterase in the acute toxicity of paraoxon, TEPP, and parathion.
A R MAIN
Canadian journal of biochemistry and physiology, 34(2), 197-216 (1956-03-01)
J U Patel et al.
Journal of pharmaceutical sciences, 83(10), 1477-1481 (1994-10-01)
An O-(saccharinylmethyl) prodrug was synthesized to improve the poor oral potency of the phenolic drug 17 beta-estradiol. This O-(imidomethyl) type of prodrug was designed to undergo chemical hydrolysis and to be a poor substrate for enzymatic hydrolysis. At 37 degrees
Tetraethyl pyrophosphate in the myasthenia gravis.
O J NOVOTA
Missouri medicine, 49(2), 133-134 (1952-02-01)
Studies on the mechanism of action of DFP and TEPP.
B P McNAMARA et al.
The Journal of pharmacology and experimental therapeutics, 110(2), 232-240 (1954-02-01)
N S L Perry et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 9(1), 48-51 (2002-04-03)
The essential oil of Salvia lavandulaefolia at two dosage levels was administered orally to rats for five days. Choline esterase activity was measured post mortem in three areas of the brain, both in the absence and presence of TEPP, a
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