33996
Ethopabate
VETRANAL®, analytical standard
Synonym(s):
Methyl 4-acetamido-2-ethoxybenzoate, Ethopabate, Ethyl pabate
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About This Item
Empirical Formula (Hill Notation):
C12H15NO4
CAS Number:
Molecular Weight:
237.25
Beilstein:
2808914
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
CCOc1cc(NC(C)=O)ccc1C(=O)OC
InChI
1S/C12H15NO4/c1-4-17-11-7-9(13-8(2)14)5-6-10(11)12(15)16-3/h5-7H,4H2,1-3H3,(H,13,14)
InChI key
GOVWOKSKFSBNGD-UHFFFAOYSA-N
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General description
Ethopabate is an antibiotic used as a coccidiostat in poultry feeds.
Application
Ethopabate may be used as a reference standard in the determination of ethopabate in feed samples using solid phase extraction with high performance liquid chromatography (SPE-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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V A Thorpe
Journal - Association of Official Analytical Chemists, 63(5), 981-984 (1980-09-01)
Medicated feeds (pelleted or mash) containing guarantees of carbadox, furazolidone, nitrofurazone, and ethopabate are pretreated with water, extracted with 95% dimethylformamide overnight at room temperature, cleaned up on a column of alumina, and injected into a high pressure liquid chromatograph
T Nagata et al.
Journal - Association of Official Analytical Chemists, 68(1), 27-28 (1985-01-01)
A liquid chromatographic (LC) method is described for determination of ethopabate residues in chicken tissues. The drug is extracted from tissues with acetonitrile, and the extract is concentrated to 2-3 mL. This aqueous solution is rinsed with ethyl acetate and
Rodrigo H M M Granja et al.
Journal of AOAC International, 91(6), 1483-1487 (2009-02-11)
Ethopabate is frequently used in the prophylaxis and treatment of coccidiosis in poultry. Residues of this drug in food present a potential risk to consumers. A simple, rapid, and sensitive column high-performance liquid chromatographic (HPLC) method with UV detection for
L R Schronk et al.
Journal - Association of Official Analytical Chemists, 60(5), 1048-1050 (1977-09-01)
A high pressure liquid chromatographic (HPLC) method is described for determining ethopabate in poultry feeds. Feed samples containing ethopabate are finely ground, extracted 30 min by sonification with methanol-water (80 + 20), and filtered. The extract is cleaned up on
A C Voeten et al.
Tijdschrift voor diergeneeskunde, 103(23), 1284-1289 (1978-12-01)
A floor pen trial was carried out on broilers in 1975 to compare the anticoccidial efficacy of monensin1), 3,5 dinitro-o-toluamide2), clopidol3), amprolium + ethopabacte4), amprolium + ethopabate + sulfaquinoxaline + pyrimethamine5) and robenidine6) in the presence of untreated controls. 4,200
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