484407

1-Methoxy-2-propanol

≥99.5%

• Synonym(s): Propylene glycol methyl ether, Propyleneglycol monomethyl ether
• Linear Formula: CH₃CH(OH)CH₂OCH₃
• CAS Number: 107-98-2
• Molecular Weight: 90.12
• Beilstein: 1731270
• EC Number: 203-539-1
• MDL number: MFCD00004537
• UNSPSC Code: 12352100
• PubChem Substance ID: 57651153
• NACRES: NA.21

Properties

• vapor density: 3.12 (vs air)
• Quality Level: 200
• vapor pressure: 10.9 mmHg ( 25 °C)
• product line: ReagentPlus^®
• Assay: ≥99.5%
• form: liquid
• autoignition temp.: 532 °F
• expl. lim.: 13.8 %
• greener alternative product characteristics: Safer Solvents and Auxiliaries; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• impurities: ≤0.001% water
• refractive index: n20/D 1.403 (lit.)
• bp: 118-119 °C (lit.)
• mp: -97 °C
• solubility: water: miscible
• density: 0.916 g/mL at 25 °C (lit.)
• application(s): microbiology
• greener alternative category: , Aligned
• SMILES string: CC(O)COC
• InChI: 1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3
• InChI key: ARXJGSRGQADJSQ-UHFFFAOYSA-N

Description

General description

1-Methoxy-2-propanol (Propylene glycol methyl ether, PGME), a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts. Its degradation by microorganisms in different soil types has been investigated. An oral reference dose (RfD) and an inhalation reference concentration (RfC) values of PGME have been obtained from inhalation studies in F344 rats and B6C3F1 mice.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry.Monoethers, especially propylene glycol methyl ether (PGME), are widely used as pollution-free solvents in fine chemical synthesis in pharmaceutical, chemical and cosmetic industries and thus aligns with "Safer Solvents and Auxiliaries". Click here for more information.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H336
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 93.2 °F - closed cup
• Flash Point(C): 34 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves