Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

SMB01380

Sigma-Aldrich

4-Methoxyestrone

≥95% (HPLC), from synthetic, solid

Synonym(s):

3-Hydroxy-4-methoxyestra-1,3,5(10)-trien-17-one

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C19H24O3
CAS Number:
58562-33-7
Molecular Weight:
300.39
MDL number:
MFCD00199041
UNSPSC Code:
51111800
NACRES:
NA.25

biological source

synthetic

Quality Level

200

Assay

≥95% (HPLC)

form

solid

storage condition

(Heat sensitive)

storage temp.

2-8°C

SMILES string

C[C@@]12[C@](CCC2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C(OC)=C4CC3

General description

4-Methoxyestrone is an endogenous, naturally occurring methoxylated catechol estrogen and an estrone metabolite formed by catechol O-methyltransferase via the intermediate 4-hydroxyestrone. It has estrogenic activity similarly to estrone and 4-hydroxyestrone.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H351,H360FD,H362

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000238156
0000238157
0000226524
0000226523
0000221875

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Urinary estrogen metabolites and gastric cancer risk among postmenopausal women
Constanza M, et al.
Cancer reports (Hoboken, N.J.), 5, e1574-e1574 (2021)
Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women
Heather A, et al.
Cancer Epidemiology, Biomarkers & Prevention, 18, 2860-2868 (2009)
Individual and cyclic estrogenic profile in women: Structure and variability of the data
Bozzolino Cristina, et al.
Steroids, 150, 108432-108432 (2019)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service