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525227

Sigma-Aldrich

Celpure® P1000

meets USP/NF testing specifications

Synonym(s):

Diatomaceous earth, flux-calcined, Filter agent

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
11101527
PubChem Substance ID:
NACRES:
NA.21

Agency

meets USP/NF testing specifications

form

powder

specific activity

≤1 EU/g (endotoxin)

composition

SiO2, 98%

parameter

1.000 (Permeability(Darcy))

impurities

≤0.2% water solubles
≤2.0% acid solubles
≤4 ppm EtOH/citric acid solubles
≤50 mg non-siliceous content

particle size

1.0-2.0 mm

cation traces

As: ≤10 ppm (leachable)
Fe: ≤5 ppm (acid soluble)
Pb: ≤10 ppm (leachable)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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General description

Celpure® P1000 (Diatomaceous earth, DE) is natural amorphous silica formed from the fossilized skeletons of diatoms. It is extracted, crushed, dried and calcined with or without flux material. DE is widely used as filler in construction materials, paints and as anti-caking agent for agricultural chemicals. It has high water and oil absorption ability. The potential toxicity of different samples of DE has been assessed. DE is also employed as an adsorbent for column chromatography.

Application

For high-purity, high-throughput processes

Legal Information

Product of Imerys Filtration Minerals
Celpure is a registered trademark of Advanced Minerals Corporation

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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The global variability of diatomaceous earth toxicity: a physicochemical and in vitro investigation.
Nattrass C, et al.
Journal of Occupational Medicine and Toxicology (London, England), 10(1), 25-25 (2015)
H Checkoway et al.
British journal of industrial medicine, 50(7), 586-597 (1993-07-01)
A cohort mortality study was conducted among workers from two plants in the diatomaceous earth mining and processing industry in California. Diatomaceous earth consists of the skeletal remains of diatoms. Exposure to amorphous (non-crystalline) and crystalline silica in the form
Induction of p53-independent growth inhibition in lung carcinoma cell A549 by gypenosides.
Journal of cellular and molecular medicine (2015).
Liu JS, et al.
Journal of Cellular and Molecular Medicine, 19(7), 1697-1709 (2015)
Manipulating surface wettability and oil absorbency of diatomite depending on processing and ambient conditions.
Ozen I, et al.
Applied Surface Science, 332, 22-31 (2015)
Xiao-Li Yang et al.
Bioresource technology, 101(23), 9178-9184 (2010-08-06)
This paper examined the effect of diatomite addition on membrane fouling and process performance in an anoxic/oxic submerged membrane bioreactor (A/O MBR). Particle size distribution, molecular weight distribution and microbial activity have been investigated to characterize the sludge mixed liquor.

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