40395

α-Carotene

≥95.0% (HPLC)

• Synonym(s): (+)-α-Carotene
• Empirical Formula (Hill Notation): C₄₀H₅₆
• CAS Number: 7488-99-5
• Molecular Weight: 536.87
• Beilstein: 3227603
• MDL number: MFCD00136012
• UNSPSC Code: 12352202
• PubChem Substance ID: 329755985
• NACRES: NA.32

Properties

• Assay: ≥95.0% (HPLC)
• form: powder
• optical purity: enantiomeric excess: ≥95.0%
• mp: 183-185 °C
• λ: 2 % in methylene chloride (in hexane)
• UV absorption: λ: 445-449 nm A_max
• storage temp.: −20°C
• SMILES string: CC(/C=C/[C@H]1C(C)=CCCC1(C)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(\C=C\C2=C(C)CCCC2(C)C)C
• InChI: 1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-23,25-28,37H,15-16,24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+/t37-/m0/s1
• InChI key: ANVAOWXLWRTKGA-NTXLUARGSA-N

Description

General description

Carotenoids are natural products used in the food, animal feed, nutraceutical, and pharmaceutical industries. α-Carotene, a carotenoid with one β-ring and one ε-ring, is commonly present in the food. Orange carrots show a high concentration of α-carotene.

Application

α-Carotene may be used as a standard in high-performance liquid chromatography (HPLC) for carotenoid quantification in Corynebacterium glutamicum.

Biochem/physiol Actions

α-Carotene exhibits provitamin A activity. It can act as an efficient inhibitor than β-carotene on certain growth factors, like N-myc activity. α-Carotene serves as a good biomarker for fruit and vegetable consumption. High serum concentrations of α-carotene are associated with lower cardiovascular disease (CVD) mortality.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable