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A1542

Sigma-Aldrich

Ammonium acetate

for molecular biology, ≥98%

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About This Item

Linear Formula:
CH3CO2NH4
CAS Number:
Molecular Weight:
77.08
Beilstein:
4186741
EC Number:
MDL number:
UNSPSC Code:
12161700
eCl@ss:
39021908
PubChem Substance ID:
NACRES:
NA.25

grade

for molecular biology

Quality Level

Assay

≥98%

form

solid

pH

6.5-7.5 (25 °C, 77.1 g/L)

mp

110-112 °C (dec.) (lit.)

solubility

water: 1 g/mL, clear, colorless to faintly yellow

anion traces

chloride (Cl-): ≤5 ppm

cation traces

Fe: ≤5 ppm
heavy metals (as Pb): ≤5 ppm

application(s)

diagnostic assay manufacturing

foreign activity

DNase, RNase and protease, none detected

storage temp.

2-8°C

SMILES string

N.CC(O)=O

InChI

1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3

InChI key

USFZMSVCRYTOJT-UHFFFAOYSA-N

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Application


  • A green analytical method for the simultaneous determination of 17 perfluoroalkyl substances (PFAS) in human serum and semen by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).: This study highlights the use of ammonium acetate in chromatography as a part of a green analytical method, enhancing the detection sensitivity and specificity for environmental contaminants in biological samples (Di Giorgi et al., 2024).

  • Innovation of 6-sulfonamide-2H-chromene derivatives as antidiabetic agents targeting α-amylase, α-glycosidase, and PPAR-γ inhibitors with in silico molecular docking simulation.: Ammonium acetate is used in the synthesis and analysis of potential antidiabetic agents, demonstrating its utility in drug discovery and pharmaceutical chemistry (Thabet et al., 2024).

  • Regulation of Tetramethylpyrazine Formation by the Phenolics-Fenton Coupled Redox Cycling System.: Explores the role of ammonium acetate in regulating chemical reactions within food chemistry, impacting flavor development and food safety (Xu et al., 2024).

  • Simultaneous determination of unecritinib (TQ-B3101) and its active metabolite crizotinib in rat plasma by LC-MS/MS:An application to pharmacokinetic studies.: Utilizes ammonium acetate in liquid chromatography-mass spectrometry to enhance the analysis of pharmaceutical compounds, crucial for understanding drug metabolism and pharmacokinetics (Wang et al., 2024).

  • Combination of online hollow fiber liquid phase microextraction with smartphone-based sensing for in situ formaldehyde assay in fabric and wastewater samples.: Demonstrates an innovative use of ammonium acetate in environmental monitoring, combining it with new technologies to enhance detection capabilities in complex samples (Javadian et al., 2024).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Frontiers in cell and developmental biology, 8, 564351-564351 (2020-12-08)
Low-density lipoprotein receptor-related protein 1 (LRP1) is a large, endocytic cell surface receptor that is highly expressed by oligodendrocyte progenitor cells (OPCs) and LRP1 expression is rapidly downregulated as OPCs differentiate into oligodendrocytes (OLs). We report that the conditional deletion
S Baron-Cohen et al.
Molecular psychiatry, 20(3), 369-376 (2014-06-04)
Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor. Utilizing the Danish Historic Birth Cohort and Danish Psychiatric Central
Merja Gergov et al.
Journal of analytical toxicology, 39(5), 359-364 (2015-03-10)
This work describes a procedure to evaluate matrix effects in a combined dilution and standard addition method (SAM) using liquid chromatography-electrospray-tandem mass spectrometry. The method was validated and applied to an analysis of metformin in postmortem blood samples. The analytical
Martijs J Jonker et al.
Nucleic acids research, 42(11), e94-e94 (2014-04-29)
Structural variations in genomes are commonly studied by (micro)array-based comparative genomic hybridization. The data analysis methods to infer copy number variation in model organisms (human, mouse) are established. In principle, the procedures are based on signal ratios between test and
Suzanne L Parker et al.
Journal of pharmaceutical and biomedical analysis, 105, 39-45 (2014-12-22)
A high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, using hydrophilic interaction liquid chromatography (HILIC) chromatography for the analysis of fosfomycin in human plasma and urine, has been developed and validated. The plasma method uses a simple protein precipitation using

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