C213130

DMT-2′O-Methyl-rC(ac) Phosphoramidite

configured for ABI

• Synonym(s): N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-cytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
• Empirical Formula (Hill Notation): C₄₂H₅₂N₅O₉P
• CAS Number: 199593-09-4
• Molecular Weight: 801.86
• UNSPSC Code: 41116105
• NACRES: NA.51

Properties

• biological source: non-animal source (no BSE/TSE risk)
• product line: Proligo Reagents
• Assay: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• form: powder
• technique(s): oligo synthesis: suitable
• impurities: ≤0.1% single unspecified Impurity (reversed phase HPLC); ≤0.3% mC2 (reversed phase HPLC, Hydrolysate); ≤0.3% mC3 (reversed phase HPLC, DMT-rC(ac)me); ≤0.3% mC4 (reversed phase HPLC, DMT-rC(ac)me-Ac); ≤0.3% water content (Karl Fischer); ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR); ≤1.0% mC1 (reversed phase HPLC, DMT-rC(ac)me-DMT); ≤3% residual Solvent content
• color: white to off-white
• λ: conforms (UV/VIS Identity)
• suitability: conforms to structure for H-NMR; conforms to structure for LC-MS
• compatibility: configured for ABI
• nucleoside profile: base: cytidine; base protecting group: acetyl; 2' protecting group: methyl; 5' protecting group: DMT; deprotection: standard
• storage temp.: 2-8°C
• InChI: 1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(54-26-12-24-43)56-38-36(55-40(39(38)52-8)46-25-23-37(44-30(5)48)45-41(46)49)27-53-42(31-13-10-9-11-14-31,32-15-19-34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H,12,26-27H2,1-8H3,(H,44,45,48,49)/t36-,38-,39?,40-,57?/m1/s1
• InChI key: WNWUMIPFLOKTEZ-IXZONTHDSA-N

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2