G4921

Anti-Granulocyte Colony Stimulating Factor antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-G-CSF
• MDL number: MFCD00211951
• UNSPSC Code: 51111800
• NACRES: NA.41

Properties

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: mouse
• technique(s): neutralization: suitable; western blot: 0.1-0.2 μg/mL
• UniProt accession no.: P09920
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Csf3(12985)

Description

Immunogen

purified, recombinant mouse granulocyte colony stimulating factor, expressed in E. coli.

Biochem/physiol Actions

Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The main functions of G-CSF include the generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves