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Key Documents

M266

Sigma-Aldrich

Anti-Glutamate Receptor NMDAR2C (NR2C) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-GluN2C, Anti-NMDAR2C, Anti-NR2C

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

mol wt

antigen 140 kDa (NR2C subunit)
antigen 180 kDa (NR2A and NR2B bands)

species reactivity

rat, human, mouse

technique(s)

immunohistochemistry (frozen sections): 1:1000
immunoprecipitation (IP): 3 μL using 200 μg of rat cerebellum.
indirect immunofluorescence: 1:1000 using frozen sections
western blot: 1:1000 using 200 μg cell lysate

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GRIN2C(2905)
mouse ... Grin2c(14813)
rat ... Grin2c(24411)

Immunogen

N-terminal portion of NR2C (amino acids 25-130)

Physical form

Lyophilized from ammonium bicarbonate (5 mM).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Stéphane Peineau et al.
Methods in molecular biology (Clifton, N.J.), 1677, 253-263 (2017-10-08)
Proving endogenous GluN presence and functions in microglia require complementary steps to demonstrate (1) that GluN genes are transcripted and translated, (2) their cellular localization, (3) that the GluN are functional, and (4) the role of the functional GluN. The

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