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N4286

Sigma-Aldrich

NU2058

>98% (HPLC)

Synonym(s):

O6-Cyclohexylmethylguanine

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About This Item

Empirical Formula (Hill Notation):
C12H17N5O
CAS Number:
161058-83-9
Molecular Weight:
247.30
MDL number:
MFCD05664734
UNSPSC Code:
12352200
PubChem Substance ID:
24724549
NACRES:
NA.77

Assay

>98% (HPLC)

form

solid

color

white

solubility

DMSO: 22 mg/mL
H2O: soluble

storage temp.

2-8°C

SMILES string

Nc1nc(OCC2CCCCC2)c3nc[nH]c3n1

InChI

1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17)

InChI key

MWGXGTJJAOZBNW-UHFFFAOYSA-N

Gene Information

human ... CDK2(1017)

Biochem/physiol Actions

Selective cyclin-dependent kinase-2 (CDK2) inhibitor.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Evgenia Lampropoulou et al.
Scientific reports, 8(1), 5893-5893 (2018-04-14)
Pleiotrophin (PTN) stimulates endothelial cell migration through binding to receptor protein tyrosine phosphatase beta/zeta (RPTPβ/ζ) and ανβ3 integrin. Screening for proteins that interact with RPTPβ/ζ and potentially regulate PTN signaling, through mass spectrometry analysis, identified cyclin-dependent kinase 5 (CDK5) activator

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