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Key Documents

SAB4700603

Sigma-Aldrich

Monoclonal Anti-Kappa light chains antibody produced in mouse

clone A8B5, purified immunoglobulin, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

A8B5, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... IGK@(50802)

General description

Immunoglobulin κ locus (IGK), also known as IGK@, is encoded by the gene mapped to human chromosome 2p11.2.
The antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Biochem/physiol Actions

Mutations in the IGK@ gene increases the risk of susceptibility to nasopharyngeal carcinoma, gastric cancer and breast cancer.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nomenclature of the human immunoglobulin kappa (IGK) genes.
Lefranc MP
Experimental and Clinical Immunogenetics, 18, 161-174 (2001)
The polymorphisms on Igkappa gene are related to susceptibility of breast cancer and gastric cancer.
Hu D
Genetic testing, 12, 575-580 (2008)

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