SML1101

Nedocromil sodium

≥98% (HPLC)

• Synonym(s): 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid sodium salt, Nedocromil disodium salt
• Empirical Formula (Hill Notation): C₁₉H₁₅NO₇ · 2 Na
• CAS Number: 69049-74-7
• Molecular Weight: 415.30
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: , white to beige to brown
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: 2-8°C
• InChI: 1S/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2
• InChI key: JQEKDNLKIVGXAU-UHFFFAOYSA-L

Description

Biochem/physiol Actions

Nedocromil is a mast cell stabilizer and anti-inflammatory and anti-allergic drug. Nedocromil inhibits the degranulation of mast cells, and prevents the activation of and mediator release from a variety of inflammatory cell types. Nedocromil inhibits release of histamine, leukotriene C4, and prostaglandin D2, but has no antihistamine, bronchodilator, or corticosteroid activity itself.

Nedocromil is considered to be more effective in treating asthma compared to a placebo.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable