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1012032

USP

Actein

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Shengmating

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About This Item

Empirical Formula (Hill Notation):
C37H56O11
CAS Number:
18642-44-9
Molecular Weight:
676.83
MDL number:
MFCD25371991
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

actein

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C[C@@H]1C[C@@]2([C@H]3[C@@](O3)(C)[C@@H](O)O2)O[C@]4([H])[C@@]1([H])[C@]([C@H](OC(C)=O)C[C@]5(C6)[C@@]7([H])CC[C@]8([H])[C@]56CC[C@H](O[C@]9([H])OC[C@@H](O)[C@H](O)[C@H]9O)C8(C)C)(C)[C@@]7(C)C4

InChI

1S/C35H54O9/c1-17-13-35(27-32(6,43-27)28(39)44-35)42-19-14-31(5)21-8-7-20-29(2,3)22(41-26-25(38)24(37)18(36)15-40-26)9-10-33(20)16-34(21,33)12-11-30(31,4)23(17)19/h17-28,36-39H,7-16H2,1-6H3/t17-,18-,19+,20+,21+,22?,23+,24+,25-,26+,27+,28?,30-,31+,32-,33-,34+,35?/m1/s1

InChI key

RKNTVINERUAWJC-LXVMFROXSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Actein USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Black Cohosh
  • Black Cohosh Fluidextract
  • Black Cohosh Tablets
  • Powdered Black Cohosh
  • Powdered Black Cohosh Extract

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Linda Saxe Einbond et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 15(6-7), 504-511 (2007-11-06)
The purpose of this report is to explore the growth inhibitory effect of extracts and compounds from black cohosh and related Cimicifuga species on human breast cancer cells and to determine the nature of the active components. Black cohosh fractions
Xiaoyan Pang et al.
Xenobiotica; the fate of foreign compounds in biological systems, 41(2), 112-123 (2010-10-29)
Black cohosh (BC) has been widely applied for the treatment of menopausal symptoms. However, increasing concerns about herb-drug interactions demand the need for studies on the influence of BC on cytochrome 450. Cyp3a11 in liver was induced by 7-fold in
Linda Saxe Einbond et al.
Planta medica, 72(13), 1200-1206 (2006-09-22)
The purpose of this study was to determine whether the triterpene glycosides present in black cohosh enhance the growth inhibitory effects of specific breast cancer chemotherapy agents. Black cohosh roots and rhizomes were extracted with methanol (MeOH)/water (H (2)O) and
Nobuko Sakurai et al.
Bioorganic & medicinal chemistry letters, 14(5), 1329-1332 (2004-02-26)
Actein (1), a tetracyclic triterpenoid from the rhizome of Cimicifuga racemosa (black cohosh), and 82 related triterpenoid and steroidal saponins isolated from higher plants were evaluated for anti-HIV activity as a continuing study to discover potential anti-AIDS agents from natural
Linda Saxe Einbond et al.
Anticancer research, 27(2), 697-712 (2007-05-01)
Previous studies indicate that specific extracts and the pure triterpene glycoside actein obtained from black cohosh inhibit growth of human breast cancer cells. Our aim is to identify alterations in gene expression induced by treatment with a methanolic extract (MeOH)
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