257370

7-Amino-4-methylcoumarin

99%

• Synonym(s): Coumarin 120
• Empirical Formula (Hill Notation): C₁₀H₉NO₂
• CAS Number: 26093-31-2
• Molecular Weight: 175.18
• Beilstein: 142231
• EC Number: 247-454-8
• MDL number: MFCD00006868
• UNSPSC Code: 12352103
• PubChem Substance ID: 57648146
• NACRES: NA.23

Properties

• description: chromophore for enzyme substrates
• Assay: 99%
• form: solid
• mp: 223-226 °C (lit.)
• λmax: 354 nm in ethanol
• storage temp.: 2-8°C
• SMILES string: CC1=CC(=O)Oc2cc(N)ccc12
• InChI: 1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
• InChI key: GLNDAGDHSLMOKX-UHFFFAOYSA-N

Description

General description

7-Amino-4-methylcoumarin (coumarin120) is an aminocoumarin laser dye that can emit laser in the range of 370-760 nm. It has three intermolecular hydrogen bonded structures with C-H···O and N-H····O.

Application

Coumarin 120 is used as a fluorescent labeling reagent for trace determination of enzymes. It may be used as an antibacterial agent against MDR isolates of M. tuberculosis as it impacts the cell morphology. Coumarin 120 may also be used as an electron donor (amino groups) to transfer charge in a fluorescent sensor for the detection of mercury ions in aqueous media.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves