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804592

Sigma-Aldrich

Bovine Collagen Solution

Type I, 3 mg/mL, ≥95%, sterile filtered, BSE-Free, suitable for biomedical research

Synonym(s):

Collagen I

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About This Item

CAS Number:
9007-34-5
UNSPSC Code:
12162002
NACRES:
NA.23

Assay

≥95%

form

liquid

concentration

3 mg/mL

shipped in

wet ice

storage temp.

2-8°C

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General description

  • Highly purified bovine corium pepsin solubilized collagen, atelo collagen, in 0.01 N HCl, pH 2. Predominantly Type I collagen with approximately 5% Type III at 3 mg/ml.
  • Sterile filtered.
  • BSE-Free.
  • ≥95% purity by SDS PAGE.
Bovine Collagen Solution can be used to form 3D structures for culturing or coating plastic labware for increased cell adhesion. It can form a gel at pH 7 and is ideal for 3D biomaterial scaffolds for cell culture, engineering tissue, and drug delivery.

Application

Forms a gel at pH 7 and is ideal for 3D biomaterial scaffolds for cell culture, engineering tissue, and drug delivery.

Legal Information

Product of Collagen Solutions.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wallace D, et al.
Advanced Drug Delivery Reviews, 55, 1631-1649 (2003)
Luo Z, et al.
Angewandte Chemie (International Edition in English), 50, 640-643 (2011)
Bareil RP, et al.
Materials, 3, 1863-1887 (2010)
Qun Zhang et al.
Stem cell research & therapy, 11(1), 407-407 (2020-09-20)
In recent years, significant progress has been made in developing highly complex tissue-engineered skin substitutes (TESSs) for wound healing. However, the lack of skin appendages, such as hair follicles and sweat glands, and the time required, are two major limitations
David Olagnier et al.
Nature communications, 11(1), 4938-4938 (2020-10-04)
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 are urgently required. Here, we demonstrate that the NRF2 antioxidant gene expression pathway is suppressed in biopsies obtained from COVID-19 patients. Further, we

Articles

Collagen in Gene Delivery Applications

Collagen-based delivery systems effectively deliver a range of viral and non-viral gene carriers by providing spatiotemporal control over delivery and reducing degradation rates and immune responses.

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Collagen molecules play a critical role in tissue architecture and strength, and in cell-matrix interactions as insoluble ligands to regulate the diverse phenotypic activities of cells.

Controlled Fabrication Methods for Tissue Engineering Constructs

Highlighting existing and novel fabrication methods for both, solid and hydrogel-based scaffold for tissue engineering applications.

Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

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