922684
N-Methyl-O-nosylhydroxylammonium triflate
Synonym(s):
NsONH2Me·OTf
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C8H9F3N2O8S2
CAS Number:
Molecular Weight:
382.29
UNSPSC Code:
12352101
Recommended Products
Application
N-Methyl-O-nosylhydroxylammonium triflate is a reagent used in iron catalyzed synthesis of N-methylamines from simple arenes. This reagent can be used to form various aryl amines without the use of precious metal catalysts, harsh conditions or complex multi-step syntheses, and represents a more robust alternative to other coupling methods of forming sp2 C-N bonds.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Org. Perox. C - Skin Irrit. 2
Storage Class Code
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Synthesis of N-Alkyl Anilines from Arenes via Iron-Promoted Aromatic C-H Amination.
Falk, et al.
Organic Letters, 23, 1422-1426 (2021)
Eric Falk et al.
Organic letters, 23(4), 1422-1426 (2021-02-06)
We report both an intermolecular C-H amination of arenes to access N-methylanilines and an intramolecular variant for the synthesis of tetrahydroquinolines. A newly developed, highly electrophilic aminating reagent was key for the direct synthesis of unprotected N-methylanilines from simple arenes.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service