H19808

3-Hydroxybenzaldehyde

≥99%

• Synonym(s): 3-Formylphenol, 5-Hydroxybenzaldehyde, m-Formylphenol, m-Hydroxybenzaldehyde
• Linear Formula: HOC₆H₄CHO
• CAS Number: 100-83-4
• Molecular Weight: 122.12
• Beilstein: 507099
• EC Number: 202-892-9
• MDL number: MFCD00003368
• UNSPSC Code: 12352100
• PubChem Substance ID: 24895491
• NACRES: NA.22

Properties

• Assay: ≥99%
• bp: 191 °C/50 mmHg (lit.)
• mp: 100-103 °C (lit.)
• SMILES string: Oc1cccc(C=O)c1
• InChI: 1S/C7H6O2/c8-5-6-2-1-3-7(9)4-6/h1-5,9H
• InChI key: IAVREABSGIHHMO-UHFFFAOYSA-N

Description

Application

3-Hydroxybenzaldehyde can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)₃ as a catalyst by Biginelli cyclocondensation reaction.
It can also be used as a starting material for the synthesis of:

• (-)-Quinocarcin, isoxazolo[3,4-e][2,1]benzisoxazole and 3-n-propylphenol.
• Oligo-3-hydroxybenzaldehyde (O-3HBA) by oxidative polycondensation.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319
• Precautionary Statements: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves