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EZML

Millipore

Mouse Leptin ELISA Kit

measures and quantifies Leptin levels in 10 μL serum or plasma

Synonym(s):

Leptin, Obesity factor

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

Mouse Leptin ELISA, This Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.

Quality Level

200

species reactivity

mouse

packaging

kit of 1 × 96 wells

parameter

10 μL sample volume (4hr assay)

assay range

accuracy: 87-100%
linearity: 100-111%
sensitivity: 0.05 ng/mL
standard curve range: 0.2-30 ng/mL

technique(s)

ELISA: suitable

input

sample type serum
sample type plasma (K2 EDTA)

UniProt accession no.

P41159
P41160

application(s)

research use

detection method

colorimetric (450nm/590nm)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

General description

Mouse Leptin ELISA is used to measure and quantify leptin levels in metabolism, endocrine, and neuroscience research. Leptin is a hormone or cytokine derived from adipocytes circulating in the blood. It acts as a regulator of food intake and energy expenditure via the hypothalamus. This hormone plays a role in angiogenesis, lipid and carbohydrate metabolism, and hematopoiesis. Leptin exerts its effects on the cardiovascular, reproductive, and immune systems. The deficiency of leptin in rodents is associated with obesity and insulin resistance.

Application

Mouse Leptin ELISA has been used to determine the levels of leptin in mice serum and plasma.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Warning

Hazard Statements

H290,H317

Hazard Classifications

Met. Corr. 1 - Skin Sens. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lin Xu et al.
The Journal of clinical investigation, 118(1), 272-280 (2007-12-22)
Leptin is a hormone that reduces excitability in some hypothalamic neurons via leptin receptor activation of the JAK2 and PI3K intracellular signaling pathways. We hypothesized that leptin receptor activation in other neuronal subtypes would have anticonvulsant activity and that intranasal
Tamiris Lima Rachid et al.
Molecular and cellular endocrinology, 402, 86-94 (2015-01-13)
Browning is characterized by the formation of beige/brite fat depots in subcutaneous white adipose tissue (sWAT). This study aimed to examine whether the chronic activation of PPARalpha by fenofibrate could induce beige cell depots in the sWAT of diet-induced obese
Timothy M Griffin et al.
Arthritis and rheumatism, 60(10), 2935-2944 (2009-10-01)
To test the hypothesis that obesity resulting from deletion of the leptin gene or the leptin receptor gene results in increased knee osteoarthritis (OA), systemic inflammation, and altered subchondral bone morphology. Leptin-deficient (ob/ob) and leptin receptor-deficient (db/db) female mice compared
Night eating and obesity in the EP3R-deficient mouse.
Manuel Sanchez-Alavez, Izabella Klein, Sara E Brownell, Iustin V Tabarean et al.
Proceedings of the National Academy of Sciences of the USA null
Effect of chronic and intermittent calorie restriction on serum adiponectin and leptin and mammary tumorigenesis.
Rogozina OP, Bonorden MJ, Seppanen CN, Grande JP, Cleary MP
Cancer Prevention Research (Philadelphia, Pa.) null
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