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Key Documents

MAB5296

Sigma-Aldrich

Anti-Oxytocin Antibody, clone 4G11

ascites fluid, clone 4G11, Chemicon®

Synonym(s):

Anti-OT, Anti-OT-NPI, Anti-OXT-NPI

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4G11, monoclonal

species reactivity

rat, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable

isotype

IgG1

NCBI accession no.

NM_000915.2

UniProt accession no.

P01178

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... OXTR(5021)

Specificity

Recognizes Oxytocin. No reactivity to arginine vasopressin, vasotocin or [Asu1,6,Arg8]-vasopressin by competitive ELISA.

Immunogen

Oxytocin conjugated to thyroglobulin.

Application

Immunohistochemistry on 4% paraformaldehyde fixed frozen tissue: 1:5,000-1:10,000.

ELISA: 1:1,000,000

Optimal working dilutions must be determined by the end user.
This Anti-Oxytocin Antibody, clone 4G11 is validated for use in ELISA, IH for the detection of Oxytocin.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mariela Mitre et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(8), 2517-2535 (2016-02-26)
Oxytocin is a neuropeptide important for social behaviors such as maternal care and parent-infant bonding. It is believed that oxytocin receptor signaling in the brain is critical for these behaviors, but it is unknown precisely when and where oxytocin receptors
Peimin Zhu et al.
The Journal of biological chemistry, 284(34), 22878-22887 (2009-06-23)
It is well established that CpG promotes pro-inflammatory cytokine and antibody production by B cells via the Toll-like receptor 9 (TLR9)-dependent pathway. However, scavenger receptors (SRs) are also capable of binding such pathogen-derived molecules, yet their contribution to CpG-induced signaling
Catherine E Barrett et al.
Neuropharmacology, 85, 357-366 (2014-06-14)
The melanocortin receptor (MCR) system has been studied extensively for its role in feeding and sexual behavior, but effects on social behavior have received little attention. α-MSH interacts with neural systems involved in sociality, including oxytocin, dopamine, and opioid systems.
Ranjan K Roy et al.
Communications biology, 1, 160-160 (2018-10-16)
Myocardial infarction (MI) initiates an increase in cardiac sympathetic nerve activity (SNA) that facilitates potentially fatal arrhythmias. The mechanism(s) underpinning sympathetic activation remain unclear. Some neuronal populations within the hypothalamic paraventricular nucleus (PVN) have been implicated in SNA. This study
Yuko Maejima et al.
Scientific reports, 9(1), 18360-18360 (2019-12-05)
Body weight (BW) is regulated in age-dependent manner; it continues to increase during growth period, and reaches a plateau once reaching adulthood. However, its underlying mechanism remains unknown. Regarding such mechanisms in the brain, we here report that neural circuits from
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