MAB8905
Anti-Measles Blend Antibody, hemagglutinin, clones CV1, CV4
ascites fluid, Chemicon®, from mouse
Synonym(s):
Rubeola
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About This Item
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biological source
mouse
Quality Level
antibody form
ascites fluid
clone
CV1, monoclonal
CV4, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
isotype
IgG1
shipped in
wet ice
Specificity
A blend of two monoclonal antibodies that recognize the measles hemagglutinin protein by indirect immunofluorescence.
Immunogen
Epitope: hemagglutinin
Hemagglutinin protein obtained from Chicago wild type strain of measles
Application
Indirect immunofluorescence at 1:100-1:1,000 using acetone fixation.
Immunohistochemistry on paraffin embedded sections (Grote et al., 2001).
Final working dilutions must be determined by end user.
Immunohistochemistry on paraffin embedded sections (Grote et al., 2001).
Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
This Anti-Measles Blend Antibody, hemagglutinin, clones CV1, CV4 is validated for use in IF, IH(P) for the detection of Measles Blend.
Physical form
Liquid ascites fluid containing no preservatives.
Storage and Stability
Maintain at -20°C in convenient aliquots for up to 12 months.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Live attenuated measles virus induces regression of human lymphoma xenografts in immunodeficient mice.
Blood, 97, 3746-3754 (2001)
Journal of virology, 91(23) (2017-09-15)
The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-phenylacetyl amino-benzamide (AS-48) have similar efficacies in blocking membrane fusion and syncytium formation mediated by measles virus (MeV). Other homologues, such as Z-d-Phe, are less effective but may act through the
Sendai virus particle production: basic requirements and role of the SYWST motif present in HN cytoplasmic tail.
Virology null
Dynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (SLAM, CD150).
The Journal of Biological Chemistry null
Journal of virology, 90(1), 68-75 (2015-10-09)
Paramyxoviruses include several insidious and ubiquitous pathogens of humans and animals, with measles virus (MeV) being a prominent one. The MeV membrane fusion apparatus consists of a receptor binding protein (hemagglutinin [H]) tetramer and a fusion (F) protein trimer. Four
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