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BCR050

Benzo[e]pyrene

BCR®, certified reference material

Synonym(s):

1,2-Benzpyrene, 4,5-Benzpyrene

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About This Item

Empirical Formula (Hill Notation):
C20H12
CAS Number:
192-97-2
Molecular Weight:
252.31
Beilstein:
1911334
EC Number:
205-892-7
MDL number:
MFCD00003605
UNSPSC Code:
41116107
PubChem Substance ID:
329774203
NACRES:
NA.24

grade

certified reference material

Agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

177-180 °C (lit.)

format

neat

storage temp.

2-8°C

SMILES string

c1ccc2c(c1)c3cccc4ccc5cccc2c5c34

InChI

1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H

InChI key

TXVHTIQJNYSSKO-UHFFFAOYSA-N

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Analysis Note

For more information please see:
BCR050

Legal Information

BCR is a registered trademark of European Commission

Pictograms

Health hazardEnvironment
GHS08,GHS09

Signal Word

Danger

Hazard Statements

H350,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ashish Sharma et al.
Investigative ophthalmology & visual science, 49(11), 5111-5117 (2008-07-01)
To better understand the cellular and molecular basis for the epidemiologic association between cigarette smoke and age-related macular degeneration (AMD), the authors examined the effects of Benzo(e)Pyrene (B(e)P), a toxic element in cigarette smoke, on human retinal pigment epithelial cells
Lawrence R Curtis et al.
Toxicology and applied pharmacology, 254(1), 1-7 (2011-05-10)
This study assessed the role of aryl hydrocarbon receptor (AHR) affinity, and cytochrome P4501A (CYP1A) protein and activity in polyaromatic hydrocarbon (PAH)-induced oxidative stress. In the 1-100nM concentration range benzo[a]pyrene (BaP) but not benzo[e]pyrene (BeP) competitively displaced 2nM [(3)H]2, 3
D R Davila et al.
Journal of toxicology and environmental health. Part A, 56(4), 249-261 (2000-03-08)
It has been well established that certain polycyclic aromatic hydrocarbons (PAHs), such as 7,12-dimethylbenz[a]anthracene (DMBA), 3-methylcholanthrene (3MC), and benzo[a]pyrene (BaP), produce immunotoxicity and cancer in rodents and that these effects are also likely seen in humans. Our laboratory has found
A Jayaprakash Patil et al.
Current eye research, 34(8), 672-682 (2009-11-11)
To study the effects of benzo(e)pyrene (B(e)P), a toxic component of cigarette smoke, on retinal neurosensory (R28) cells and human microvascular endothelial cells (HMVEC). R28 cells and HMVEC were treated for 24 hours with 1000, 400, 200, and 100 micro
J A Hardin et al.
Toxicology and applied pharmacology, 117(2), 155-164 (1992-12-01)
The capacity for polycyclic aromatic hydrocarbons (PAH) to suppress immune cell function has been well documented. Nevertheless, mechanisms responsible for PAH immunosuppression and potential effects of PAH on lymphocyte development (lymphopoeisis) remain poorly defined. Murine bone marrow cultures were used
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