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P2472

Sigma-Aldrich

Povidone

meets USP testing specifications

Synonym(s):

Polyvinylpyrrolidone, PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
MDL number:
MFCD00149016
UNSPSC Code:
12161900
PubChem Substance ID:
24898327
NACRES:
NA.21

Agency

USP/NF
meets USP testing specifications

Quality Level

200

description

K-value 29 - 32

form

powder

application(s)

pharmaceutical (small molecule)

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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Application


  • Polyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer.: This study highlights the application of povidone (PVP) in the synthesis of multifunctional nanodrugs, showcasing its role in stabilizing nanoparticles for targeted cancer therapy. The findings emphasize PVP′s crucial function in enhancing the bioavailability and therapeutic efficacy of anticancer drugs (Wang C et al., 2024).

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCH0458
0000316939
0000316941
SLCH0458
0000316939

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X C Qin et al.
Journal of photochemistry and photobiology. B, Biology, 120, 156-162 (2013-01-30)
Nanographene oxide (NGO), a new type of nanomaterial for anticancer drugs delivery and near-infrared (NIR)-mediated photothermal ablation of tumors, has been used in the combination of photothermal therapy and chemotherapy. Herein, targeted chemo-photothermal therapy based on polyvinylpyrrolidone (PVP) functionalized NGO
Sung Neung Lee et al.
Archives of pharmacal research, 36(1), 79-85 (2013-01-19)
A novel surface-attached, spray-dried solid dispersion containing poorly water-soluble carvedilol (CV) without any change in the crystallinity was prepared using water, polyvinylpyrrolidone (PVP K30) and Tween 80. The solid dispersion was optimized by investigating the effects of the weight ratios
Yan-Yan Yin et al.
Inorganic chemistry, 52(7), 3738-3743 (2013-03-20)
Both bulk crystals and nanocrystals of two helical complexes, [Cu(μ2-L)(H2O)]n (1) and {[Cu(μ2-L)(H2O)]·2H2O}n (2) (H2L = thiazolidine-2,4-dicarboxylic acid), have been synthesized with the chiralities of right-handedness (1) and left-handedness (2), respectively. 4-Cyanopyridine and poly(vinylpyrrolidone) (PVP) have been applied to control
Helen Thomas et al.
Journal of chromatography. A, 1285, 48-56 (2013-03-16)
In protein chromatography, the size of the protein determines which fraction of pores it can access within a resin and at which rate of diffusion. Moreover, in the presence of grafted polymers like in advanced materials, adsorbed proteins and electrolytes
S Fardindoost et al.
Nanotechnology, 24(13), 135201-135201 (2013-03-13)
In this paper we present experimental results describing electrical readout of the mechanical vibratory response of graphene-doped fibers by employing electrical actuation. For a fiber resonator with an approximate radius of 850 nm and length of 100 μm, we observed a resonance
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