Skip to Content
Merck
All Photos(5)

Key Documents

View All Documentation

P45907

Sigma-Aldrich

Piperazine

ReagentPlus®, 99%

Synonym(s):

1,4-Diazacyclohexane, Diethylenediamine

Sign Into View Organizational & Contract Pricing
All Photos(5)

About This Item

Empirical Formula (Hill Notation):
C4H10N2
CAS Number:
110-85-0
Molecular Weight:
86.14
Beilstein:
102555
EC Number:
203-808-3
MDL number:
MFCD00005953
UNSPSC Code:
12352100
eCl@ss:
39160301
PubChem Substance ID:
24898556
NACRES:
NA.21

vapor pressure

0.8 mmHg ( 20 °C)

Quality Level

200

product line

ReagentPlus®

Assay

99%

form

solid

expl. lim.

14 %

impurities

<1% water

pH

10.8-11.8 (100 g/L)

bp

145-146 °C (lit.)

mp

109-112 °C (lit.)

solubility

H2O: 0.9 g/L at 20 °C

SMILES string

C1CNCCN1

InChI

1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2

InChI key

GLUUGHFHXGJENI-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Piperazine (PZ) is an amine solvent. The ability of aqueous PZ to absorb carbon dioxide (CO2) has been assessed. It is reported to cause paralysis in Ascaris worms. The analysis of the crystal structure of PZ at 150K shows the presence of layered structure with NH...N hydrogen-bonded chains.

Application

Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.
Piperazine may be used in the preparation of N-(hetero)arylpiperazines.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Sol. 1 - Repr. 2 - Resp. Sens. 1B - Skin Corr. 1B - Skin Sens. 1B

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW0731
STBL0983
MKCT5522
STBK9211
MKCR9407

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

1-Iodo-4-nitrobenzene 98%

Sigma-Aldrich

I9805

1-Iodo-4-nitrobenzene

2-Methylpiperazine 95%

Sigma-Aldrich

M72404

2-Methylpiperazine

Carbon dioxide capture with concentrated, aqueous piperazine.
Freeman SA, et al.
International Journal of Greenhouse Gas Control, 4(2), 119-124 (2010)
Absorption of carbon dioxide into aqueous piperazine: reaction kinetics, mass transfer and solubility.
Bishnoi S and Rochelle GT.
Chemical Engineering Science, 55(22), 5531-5543 (2000)
Synthesis of N-arylpiperazines from aryl halides and piperazine under a palladium tri-tert-butylphosphine catalyst.
Nishiyama M, et al.
Tetrahedron Letters, 39(7), 617-620 (1998)
Investigations on the action of piperazine on Ascaris lumbricoides.
Norton S and De Beer EJ.
The American Journal of Tropical Medicine and Hygiene, 6(5), 898-905 (1957)
Andrew Parkin et al.
Acta crystallographica. Section B, Structural science, 60(Pt 2), 219-227 (2004-03-16)
The crystal structures of piperazine, piperidine and morpholine have been determined at 150 K. All three structures are characterized by the formation of NH...N hydrogen-bonded chains. In piperazine these are linked to form sheets, but the chains are shifted so
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service