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S6546

Sigma-Aldrich

Sodium chloride solution

5 M

Synonym(s):

Halite, NaCl, sodium chloride

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About This Item

Linear Formula:
NaCl
CAS Number:
Molecular Weight:
58.44
Beilstein:
3534976
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.25

sterility

0.2 μm filtered

Quality Level

concentration

5 M

density

1.190 g/cm3

SMILES string

[Na+].[Cl-]

InChI

1S/ClH.Na/h1H;/q;+1/p-1

InChI key

FAPWRFPIFSIZLT-UHFFFAOYSA-M

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General description

Sodium chloride (NaCl), common salt also known as halite, is ubiquitous in occurrence and has many vital applications. It is a white crystalline solid, fairly soluble in water. NaCl is a flavouring agent in the food industry and used for texturing bread and baked foods. NaCl is an essential salt for normal body functions in humans and animals. NaCl is essential for maintaining plasma osmolality and extracellular fluid volume of the body. Excess of NaCl leads to elevated blood pressure which has implications on cardiovascular and renal diseases. NaCl is a basic component in the microbiological medium, specifically for culturing of halophiles. Sterile NaCl is a constituent of eye drop solutions.

Application

Sodium chloride has been used:
  • as a supplement in serum free media for CA3 pyramidal neuron layer preparation
  • in the preparation of oligonucleotides (ODNs) annealing buffer
  • in the preparation of phosphate buffered saline and in phosphatase methylesterase-1 (PME-1) inhibition and counterscreen assay buffers

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The Actions and Uses of Ophthalmic Drugs: A Textbook for Students and Practitioners (2013)
Salt, chlor-alkali and related heavy chemicals
Kent and Riegel's Handbook of Industrial Chemistry and Biotechnology (2010)
Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate (2005)
Probe Reports from the NIH Molecular Libraries Program (2010)
Simultaneous reprogramming and gene editing of human fibroblasts
Howden SE, et al.
Nature Protocols, 13(5), 875-875 (2018)

Protocols

Enzymatic Assay of Sulfatase (EC 3.1.6.1.)

To measure collagenase activity, N-(3-[2-Furyl]acryloyl)-Leu-Gly-Pro-Ala is used in a continuous spectrophotometric rate determination at 345 nm. Collagenase hydrolyzes collagen peptide bonds.

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