537721

3-Methyl-2-butanone

99%

• Synonym(s): Isopropyl methyl ketone, Methyl isopropyl ketone
• Linear Formula: (CH₃)₂CHCOCH₃
• CAS Number: 563-80-4
• Molecular Weight: 86.13
• Beilstein: 1071238
• EC Number: 209-264-3
• MDL number: MFCD00008919
• UNSPSC Code: 12352115
• PubChem Substance ID: 329757993
• NACRES: NA.21

Properties

• Assay: 99%
• form: liquid
• expl. lim.: 0.34-6.3 %
• refractive index: n20/D 1.388 (lit.)
• bp: 94-95 °C (lit.)
• mp: −92 °C (lit.)
• solubility: water: soluble 8.21 g/L at 20 °C
• density: 0.805 g/mL at 25 °C (lit.)
• SMILES string: CC(C)C(C)=O
• InChI: 1S/C5H10O/c1-4(2)5(3)6/h4H,1-3H3
• InChI key: SYBYTAAJFKOIEJ-UHFFFAOYSA-N

Description

General description

3-Methyl-2-butanone (Methyl isopropyl ketone, MIPK, isopropyl methyl ketone), an aliphatic ketone, is a volatile organic compound. Photodegradation of MIPK in gas-phase has been reported. Asymmetric hydrogenation of MIPK with high enantioselectivity in the presence of Rh-PennPhos (rhodium-P,P′-1,2-phenylenebis(endo-2,5-dialkyl-7-phosphabicyclo[2.2.1]heptane) complex has been reported.

Application

3-Methyl-2-butanone may be used to prepare (R)-3-methyl-2-butanol via asymmetric hydrogenation in the presence of a wool-Pd complex.

Safety Information

• Pictograms: GHS02
• Signal Word: Danger
• Hazard Statements: H225
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 26.6 °F - closed cup
• Flash Point(C): -3 °C - closed cup