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84110

Sigma-Aldrich

Sucrose monolaurate

BioXtra, ≥97.0% (TLC)

Synonym(s):

n-Dodecanoylsucrose, Lauric acid sucrose ester, Sucrose monododecanoate

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About This Item

Empirical Formula (Hill Notation):
C24H44O12
CAS Number:
Molecular Weight:
524.60
Beilstein:
65819
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

product line

BioXtra

Assay

≥97.0% (TLC)

form

powder

mol wt

524.60 g/mol

impurities

≤3% water

CMC

0.3

cation traces

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC(=O)OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C24H44O12/c1-2-3-4-5-6-7-8-9-10-11-17(27)33-13-16-18(28)20(30)21(31)23(34-16)36-24(14-26)22(32)19(29)15(12-25)35-24/h15-16,18-23,25-26,28-32H,2-14H2,1H3/t15-,16-,18-,19-,20+,21-,22+,23-,24+/m1/s1

InChI key

KGUHOFWIXKIURA-VQXBOQCVSA-N

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General description

Sucrose monolaurate is a non-ionic detergent and a carbohydrate fatty acid monoester. It is generally used for the solubilization of membrane proteins.

Application

Sucrose monolaurate has been used as an antimicrobial agent. It has also been used as a constituent of lysis buffer to homogenize placental tissues for determining serine palmitoyltransferase (SPT) activity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wiebke Saal et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 111, 96-103 (2017-09-26)
Solubility screening in different surfactant solutions is an important part of pharmaceutical profiling. A particular interest is in low surfactant concentrations that mimic the dilution of an oral dosage form. Despite of intensive previous research on solubilization in micelles, there
M Hekman et al.
The EMBO journal, 3(13), 3339-3345 (1984-12-20)
Beta 1-Adrenergic receptor proteins were extracted from turkey erythrocyte membranes with lauroyl sucrose and digitonin and purified by affinity chromatography on a column of alprenolol agarose Affi-gel 10 or 15. The 5000-fold purified receptor is able to couple functionally with
Detergents for extraction of visual pigments: types, solubilization, and stability.
S L Fong et al.
Methods in enzymology, 81, 133-140 (1982-01-01)
Prediction of Listeria monocytogenes ATCC 7644 growth on fresh-cut produce treated with bacteriophage and sucrose monolaurate by using artificial neural network
Oladunjoye A, et al.
LWT--Food Science and Technology, 76, 9-17 (2017)
Christopher Rupp et al.
International journal of pharmaceutics, 395(1-2), 272-280 (2010-06-29)
A remarkable part of newly developed active pharmaceutical ingredients is rejected in early phase development and will never find a way to a patient because of poor water solubility which is often paired with poor bioavailability. Considering such arising solubility

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