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Key Documents

A5862

Sigma-Aldrich

Anisomycin, Ready Made Solution from Streptomyces griseolus

10 mg/mL in DMSO

Synonym(s):

(2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate, Flagecidin

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About This Item

Empirical Formula (Hill Notation):
C14H19NO4
CAS Number:
22862-76-6
Molecular Weight:
265.30
EC Number:
200-664-3
UNSPSC Code:
51102829
NACRES:
NA.85

form

liquid

Quality Level

200

concentration

10 mg/mL in DMSO

antibiotic activity spectrum

Gram-negative bacteria

Mode of action

protein synthesis | inhibits

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m0/s1

InChI key

YKJYKKNCCRKFSL-BFHYXJOUSA-N

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Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

Certificates of Analysis (COA)

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In prokaryotes the genome is organized in a dynamic structure called the nucleoid, which is embedded in the cytoplasm. We show here that in the archaeon Haloferax volcanii, compaction and reorganization of the nucleoid is induced by stresses that damage
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(44), 15318-15327 (2012-11-02)
Loss of the RNA-binding protein fragile X mental retardation protein (FMRP) represents the most common form of inherited intellectual disability. Studies with heterologous expression systems indicate that FMRP interacts directly with Slack Na(+)-activated K(+) channels (K(Na)), producing an enhancement of
Einar Ö Einarsson et al.
Learning & memory (Cold Spring Harbor, N.Y.), 19(10), 449-452 (2012-09-18)
It has been suggested that memories become more stable and less susceptible to the disruption of reconsolidation over weeks after learning. Here, we test this by targeting the anterior cingulate cortex (ACC) and test its involvement in the formation, consolidation
Ayumi Kishioka et al.
Molecular brain, 6, 17-17 (2013-04-17)
Fear is one of the most potent emotional experiences and is an adaptive component of response to potentially threatening stimuli. Cumulative evidence suggests that the amygdala plays a central role in the acquisition, storage and expression of fear memory. We
K L Shires et al.
Nature communications, 3, 1246-1246 (2012-12-06)
In isolated hippocampal slices, decaying long-term potentiation can be stabilized and converted to late long-term potentiation lasting many hours, by prior or subsequent strong high-frequency tetanization of an independent input to a common population of neurons-a phenomenon known as 'synaptic
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