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C0985

Sigma-Aldrich

Cytidine 3′,5′-cyclic mono­phos­phate sodium salt

≥98% (HPLC)

Synonym(s):

cCMP sodium salt

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About This Item

Empirical Formula (Hill Notation):
C9H11N3O7PNa
CAS Number:
54925-33-6
Molecular Weight:
327.16
EC Number:
259-397-6
MDL number:
MFCD00037485
UNSPSC Code:
41106305
PubChem Substance ID:
329774833
NACRES:
NA.77

description

1 vial contains 50μmol or approximately 16mg

Quality Level

200

Assay

≥98% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O

InChI

1S/C9H12N3O7P.Na/c10-5-1-2-12(9(14)11-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14);/q;+1/p-1/t4-,6-,7-,8-;/m1./s1

InChI key

RZAHVNCNTLFRHJ-IAIGYFSYSA-M

Biochem/physiol Actions

Produced by the hydrolysis of cytidine 5′-triphos­phate by the enzyme cytidylyl cyclase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Newton, R.P.
Nucleosides and Nucleotides, 14, 743-743 (1995)
Xiangang Zong et al.
The Journal of biological chemistry, 287(32), 26506-26512 (2012-06-21)
Activation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated in vivo by direct binding of the second messenger cAMP. This process plays a fundamental role in the fine-tuning of HCN channel activity and is critical for the modulation of cardiac
Sameer B Shah et al.
Neurobiology of disease, 36(1), 11-25 (2009-06-06)
Microtubule-based neuronal transport pathways are impaired during the progression of Alzheimer's disease and other neurodegenerative conditions. However, mechanisms leading to defects in transport remain to be determined. We quantified morphological changes in neuronal cells following treatment with fibrils and unaggregated
Peter T W Kim et al.
PloS one, 5(11), e14146-e14146 (2010-12-15)
Pluripotent embryonic stem cells hold a great promise as an unlimited source of tissue for treatment of chronic diseases such as Type 1 diabetes. Herein, we describe a protocol using all-trans-retinoic acid, basic fibroblast growth factor and dibutyryl cAMP (DBcAMP)
Janice M W Taylor et al.
Cardiovascular research, 86(3), 526-534 (2010-01-20)
In this study, we investigated the impact of enhancing cholesterol delivery to mitochondrial sterol 27-hydroxylase, via steroidogenic acute regulatory protein (StAR), on the expression of genes involved in macrophage cholesterol homeostasis and efflux of cholesterol to apolipoprotein (apo) AI. Stably
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