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Key Documents

EDFS

Sigma-Aldrich

Ethylenediaminetetraacetic acid iron(III) sodium salt

powder

Synonym(s):

EDTA iron(III) sodium salt, Edathamil, Komplexon II

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About This Item

Linear Formula:
C10H12N2NaFeO8
CAS Number:
Molecular Weight:
367.05
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

Agency

suitable for SM 5210

form

powder

composition

Iron, 13.7-18.7% ICP
Sodium, 5.6-7.9% ICP

reaction suitability

reagent type: chelator

concentration

≥67.5% (EDTA titration)

pH

4.5

mp

80 °C

solubility

water: 50 mg/mL, clear to slightly hazy, yellow to brown

storage temp.

room temp

SMILES string

[Na+].[Fe+3].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.Fe.Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;+3;+1/p-4

InChI key

MKWYFZFMAMBPQK-UHFFFAOYSA-J

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Application

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors. Iron-EDTA enhances damage due to reactive oxygen species, such as depletion of reduced glutathione, formation of methemoglobin, and lipid peroxidation.

Legal Information

Komplexon is a trademark of CU Chemie Uetikon AG

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Natasha T Forester et al.
Molecular plant-microbe interactions : MPMI, 32(10), 1324-1335 (2019-05-21)
In ascomycetes and basidiomycetes, iron-responsive GATA-type transcriptional repressors are involved in regulating iron homeostasis, notably to prevent iron toxicity through control of iron uptake. To date, it has been unknown whether this iron regulator contributes toward mutualistic endosymbiosis of microbes
Suying Chang et al.
Food and nutrition bulletin, 33(2), 111-116 (2012-08-23)
Ferric sodium ethylenediaminetetraacetate (NaFeEDTA) enhances iron absorption in the presence of phytate. However, the amount of NaFeEDTA that would have to be added to a complementary food to provide the necessary intake of iron for an infant or young child
María J Binaghi et al.
Archivos latinoamericanos de nutricion, 61(3), 316-322 (2012-06-16)
Home-made diets are the most frequently used complementary foods. In the present work we evaluated iron and zinc availability in a usually consumed infant diet containing either iron-fortified bread with different iron sources: ferrous sulfate, ferrous bisglycinate, NaFeEDTA. We also
Bo Wang et al.
Wei sheng yan jiu = Journal of hygiene research, 40(3), 334-337 (2011-06-24)
To assess the effectiveness of social mobilization and social marketing in promoting NaFeEDTA-fortified soy sauce in an iron deficient population. This study was an uncontrolled, community-based, before-after study, which was implemented in three counties of Shijiazhuang Municipality. The intervention was
Monica N Orozco et al.
Annals of nutrition & metabolism, 60(2), 108-114 (2012-03-15)
In any context of iron supplementation in the prenatal prophylaxis or therapeutic dosage range, a large amount will remain unabsorbed and pass through the intestinal tract into the colonic digesta possibly causing increased oxidation. To compare the generation of fecal

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