G9910

Sodium glycodeoxycholate

BioXtra, ≥97% (HPLC)

• Synonym(s): 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Glycodeoxycholic acid sodium salt, Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
• Empirical Formula (Hill Notation): C₂₆H₄₂NNaO₅
• CAS Number: 16409-34-0
• Molecular Weight: 471.61
• EC Number: 240-455-4
• MDL number: MFCD00036742
• UNSPSC Code: 12161900
• PubChem Substance ID: 24895386
• NACRES: NA.25

Properties

• description: anionic
• product line: BioXtra
• Assay: ≥97% (HPLC)
• mol wt: 471.61 g/mol
• impurities: ≤0.0025% Phosphorus (P); ≤0.1% Insoluble matter
• CMC: 2.1 mM
• solubility: H₂O: 0.1 M, clear to slightly hazy, colorless to almost colorless
• anion traces: chloride (Cl^-): ≤1%; sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.0005%; Ca: ≤0.011%; Cu: ≤0.0005%; Fe: ≤0.001%; K: ≤0.005%; NH₄⁺: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.003%
• SMILES string: [Na].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@]([H])([C@H](C)CCC(=O)NCC(O)=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C26H43NO5.Na.H/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3;;/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);;/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-;;/m1../s1
• InChI key: BMYWWGPEKRLDGW-ZXMGEDLUSA-N

Description

General description

Sodium glycodeoxycholate is a bile salt that can be used to form biomimicking environments.

Application

Sodium glycodeoxycholate has been used in a study to develop more similar mimetic intestinal fluids to physiological fluids than those developed by mixed bile salt systems (MBS). It has also been used in a study to investigate Ca²⁺ buffering capability of bile salt micelles.

Biochem/physiol Actions

Induces apoptosis in hepatocytes; may induce DNA cleavage.

Other Notes

Bile Salt

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves