L2250

Lithium L-lactate

≥98% (titration)

• Synonym(s): (S)-2-Hydroxypropionic acid lithium salt, L-Lactic acid lithium salt, Sarcolactic acid lithium salt
• Empirical Formula (Hill Notation): C₃H₅LiO₃
• CAS Number: 27848-80-2
• Molecular Weight: 96.01
• Beilstein: 6127244
• EC Number: 248-692-5
• MDL number: MFCD00065512
• UNSPSC Code: 12352201
• PubChem Substance ID: 57654325
• NACRES: NA.25

Properties

• Assay: ≥98% (titration)
• form: powder
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: <2% water (Karl Fischer)
• color: white
• solubility: water: 100 mg/mL, clear, colorless
• cation traces: Li: 5.26-9.30% (anhydrous)
• application(s): food and beverages; hematology; microbiology
• storage temp.: 2-8°C
• SMILES string: [Li+].C[C@H](O)C([O-])=O
• InChI: 1S/C3H6O3.Li/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1/t2-;/m0./s1
• InChI key: GKQWYZBANWAFMQ-DKWTVANSSA-M

Description

General description

Lithium L-lactate, also known as Sarcolactic acid lithium or Lithium (S)-2-hydroxypropanoate, is a lithium salt of L-lactic acid, the optically active isomer of lactic acid characterized by an (S) stereochemical arrangement. L-Lactic acid is naturally produced in animals through the fermentation of pyruvate via lactate dehydrogenase during normal metabolism and exercise. This compound is a crucial element in lactic acid fermentation carried out by lactic acid bacteria, where carbohydrates are converted into lactic acid. In humans, lactic acid and its conjugate base play vital roles in various biological processes, spanning from prenatal development to the maintenance of the extracellular fluid surrounding neurons.

Recent research indicates that Lithium L-lactate exhibits mood-stabilizing effects, particularly in individuals with bipolar disorder. This impact is believed to be linked to its influence on the phosphatidylinositol (PI) pathway and the inhibition of glycogen synthase kinase-3 (GSK-3) activity. Beyond bipolar disorder, ongoing investigations are exploring the potential applications of Lithium L-lactate in neuropsychiatric conditions, including studies related to depression, anxiety, and schizophrenia, highlighting its significance in the areas of metabolomics and biochemical research.

Application

Lithium L-lactate has been used as a standard:

• for the quantification of lactic acid using analytical methods
• for the quantification of lactic acid using high-performance liquid chromatography
• as a standard for L-lactic acid assay

Lithium L-lactate is a versatile compound that finds application in metabolomics and biochemical research.

Features and Benefits

• Ideal for Metabolomics, Biochemical and Cell Biology research
• Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves