O2378

Oxymetazoline hydrochloride

≥99%, solid

• Synonym(s): 2-(3-Hydroxy-2,6-dimethyl-4-t-butylbenzyl)-2-imidazoline hydrochloride
• Empirical Formula (Hill Notation): C₁₆H₂₄N₂O · HCl
• CAS Number: 2315-02-8
• Molecular Weight: 296.84
• EC Number: 219-015-0
• MDL number: MFCD00058147
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277792
• NACRES: NA.77

Properties

• Assay: ≥99%
• form: solid
• solubility: H₂O: soluble; alcohol: soluble
• originator: Schering Plough
• SMILES string: Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C
• InChI: 1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
• InChI key: BEEDODBODQVSIM-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , HTR1A(3350) , HTR1B(3351) , HTR1D(3352)

Description

Biochem/physiol Actions

Oxymetazoline hydrochloride is a partial α_2A-adrenoceptor agonist; agonist at 5-HT_1A, 5-HT_1B, and 5-HT_1D serotonin receptors. It is a mixed agonist-antagonist at 5-HT_1C serotonin receptors.

Features and Benefits

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H300 + H330,H318,H412
• Precautionary Statements: P260 - P264 - P273 - P280 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
• Storage Class Code: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3