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Key Documents

1623604

USP

Succinylmonocholine chloride

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-(3-Carboxy-1-oxopropoxy)-N,N,N-trimethylethanaminium chloride

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About This Item

Empirical Formula (Hill Notation):
C9H18ClNO4
CAS Number:
5297-17-6
Molecular Weight:
239.70
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

succinylcholine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C9H17NO4.ClH/c1-10(2,3)6-7-14-9(13)5-4-8(11)12;/h4-7H2,1-3H3;1H

InChI key

LDHMZIUMVSRSIK-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Succinylmonocholine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monograph such as Succinylcholine Chloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Succinylmonocholine identified in negative control tissues.
Marc LeBeau et al.
Journal of analytical toxicology, 27(8), 600-601 (2003-12-17)
M M Andrews et al.
The Journal of pharmacy and pharmacology, 39(3), 173-179 (1987-03-01)
The effects of equimolar concentrations (3.0 X 10(-5) M) of succinylcholine (SCh) and succinylmonocholine (SMC) were studied in-vitro at 20 degrees C in rat extensor digitorum longus muscle (EDL) 0-147 days after common peroneal nerve section. Analysis of simultaneous measurements
Uta Kuepper et al.
Rapid communications in mass spectrometry : RCM, 22(12), 1965-1970 (2008-05-21)
The determination and quantitation of drugs in biological matrices using high-performance liquid chromatography/tandem mass spectrometry (HPLC/MS/MS) is becoming increasingly popular in analytical toxicology, while at the same time a growing awareness for the limits of this technique can be observed.
Uta Kuepper et al.
International journal of legal medicine, 126(2), 259-269 (2011-09-29)
The muscle relaxant succinylcholine (SUX) evokes respiratory paralysis, and numerous cases of fatal SUX intoxication have been reported. Detection of SUX and its metabolite succinylmonocholine (SMC) is difficult, both due to their (bis-) quaternary structure and the extreme hydrolytic susceptibility
Uta Kuepper et al.
Journal of analytical toxicology, 35(5), 302-311 (2011-05-31)
Intoxications with succinylcholine (SUX) lead to a potentially lethal respiratory paralysis, and forensic cases involving accidental or deliberate SUX-application have been reported. Detection of SUX as well as its metabolite succinylmonocholine (SMC) is difficult: both substances are analytically challenging, and
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