E1279
Enoximone
solid
Sinónimos:
1,3-Dihydro-4-methyl-5-(4-methylthiobenzoyl)-2H-imidazol-2-one
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Fórmula empírica (notación de Hill):
C12H12N2O2S
Número CAS:
Peso molecular:
248.30
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Form:
solid
Quality level:
Servicio técnico
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Permítanos ayudarleform
solid
Quality Level
color
light yellow
solubility
DMSO: soluble 28 mg/mL
SMILES string
CSc1ccc(cc1)C(=O)C2=C(C)NC(=O)N2
InChI
1S/C12H12N2O2S/c1-7-10(14-12(16)13-7)11(15)8-3-5-9(17-2)6-4-8/h3-6H,1-2H3,(H2,13,14,16)
InChI key
ZJKNESGOIKRXQY-UHFFFAOYSA-N
Gene Information
human ... PDE3A(5139), PDE3B(5140)
Biochem/physiol Actions
Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart.
Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Artículos
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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To investigate the influence of calcium chloride (CaCl(2)) on the cardio-respiratory effects of enoximone in isoflurane anaesthetized ponies. Prospective consecutive experimental trial. Animals Six healthy ponies, weighing 287 +/- 55 kg were included in this study. After sedation (romifidine, 80
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Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| E1279-10MG | 04061833629697 |
| E1279-50MG | 04061833629703 |